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ANCA associated vasculitis is a serious, very often recurrent disease that despite the current standard treatment with high-dose glucocorticoids and either cyclophosphamide or rituximab, patients have a nine-fold increased...

ANCA vasculitis C5 and C5aR Complement target therapy Animals Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Complement Activation Complement System Proteins cyclophosphamide Glucocorticoids Humans Rituximab