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The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways.
Milton Pereira, Danielle F Durso, Clare E Bryant, Evelyn A Kurt-Jones, Neal Silverman, Douglas T Golenbock, Ricardo T Gazzinelli
Sep 17, 2022
CP: Immunology Gram-negative IRAK LPS NF-kB TLR TRAF6 Toll-like receptor Cell Signaling innate immunity macrophage Adaptor Proteins Signal Transducing Adaptor Proteins Vesicular Transport Humans Interleukin-1 Receptor-Associated Kinases Myeloid Differentiation Factor 88 Signal Transduction Toll-Like Receptor 3 Toll-Like Receptor 4