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Inhibition of Mitochondrial Redox Signaling with MitoQ Prevents Metastasis of Human Pancreatic Cancer in Mice.
Tania Capeloa, Justine A Van de Velde, Donatienne d'Hose, Sara G Lipari, Françoise Derouane, Loïc Hamelin, Marie Bedin, Thibaut Vazeille, François P Duhoux, Michael P Murphy, Paolo E Porporato, Bernard Gallez, Pierre Sonveaux
Nov 15, 2022
Collagen VI expression is negatively mechanosensitive in pancreatic cancer cells and supports the metastatic niche.
Vasileios Papalazarou, James Drew, Amelie Juin, Heather J Spence, Jamie Whitelaw, Colin Nixon, Manuel Salmeron-Sanchez, Laura M Machesky
Dec 22, 2022
Inhibition of Mitochondrial Redox Signaling with MitoQ Prevents Metastasis of Human Pancreatic Cancer in Mice.
Tania Capeloa, Justine A Van de Velde, Donatienne d'Hose, Sara G Lipari, Françoise Derouane, Loïc Hamelin, Marie Bedin, Thibaut Vazeille, François P Duhoux, Michael P Murphy, Paolo E Porporato, Bernard Gallez, Pierre Sonveaux
Nov 16, 2022
At diagnosis, about 35% of pancreatic cancers are at the locally invasive yet premetastatic stage. Surgical resection is not a treatment option, leaving patients with a largely incurable disease that often evolves to the...