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Integrated chromosomal and plasmid sequence analyses reveal diverse modes of carbapenemase gene spread among Klebsiella pneumoniae.
Sophia David, Victoria Cohen, Sandra Reuter, Anna E Sheppard, Tommaso Giani, Julian Parkhill, European Survey of Carbapenemase-Producing Enterobacteriaceae (EuSCAPE) Working Group, ESCMID Study Group for Epidemiological Markers (ESGEM), Gian Maria Rossolini, Edward J Feil, Hajo Grundmann, David M Aanensen
Dec 16, 2020
Molecular and genomic surveillance systems for bacterial pathogens currently rely on tracking clonally evolving lineages. By contrast, plasmids are usually excluded or analyzed with low-resolution techniques, despite being the...
Klebsiella pneumoniae carbapenem resistance carbapenemase genes Genomics Plasmids Anti-Bacterial Agents Bacterial Proteins Carbapenems Cell Lineage Chromosomes Bacterial Drug Resistance Multiple Bacterial Genome Bacterial Humans Klebsiella Infections Klebsiella pneumoniae Plasmids Sequence Analysis DNA beta-Lactamases
Epidemiology, Outcomes and Resource Utilisation in Patients with Carbapenem Non-susceptible Gram-Negative Bacteria in the UK
Simon D Goldenberg, Andrew R Dodgson, Gavin Barlow, Benjamin J Parcell, Lim Jones, Mahableshwar Albur, A Peter R Wilson, David A Enoch, Aleks Marek, Christianne Micallef, Davide Manissero, Christopher Longshaw, Sara Lopes, Karan Gill
Jul 25, 2022