Optimal protamine dosing after cardiopulmonary bypass
Lachlan F Miles,
Christiana Burt,
Joseph Arrowsmith,
Mikel A Mckie,
Sofia S Villar,
Pooveshnie Govender,
Ruth Shaylor,
Zihui Tan,
Ravi de Silva,
Florian Falter
Jun 17, 2021
BACKGROUND: The dose of protamine required following cardiopulmonary bypass (CPB) is often determined by the dose of heparin required pre-CPB, expressed as a fixed ratio. Dosing based on mathematical models of heparin clearance...