Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity.
Marie-Therese Rached,
Steven J Millership,
Silvia MA Pedroni,
Agharul I Choudhury,
Ana SH Costa,
Darran G Hardy,
Justyna A Glegola,
Elaine E Irvine,
Colin Selman,
Megan C Woodberry,
Vijay K Yadav,
Sanjay Khadayate,
Antonio Vidal-Puig,
Samuel Virtue,
Christian Frezza,
Dominic J Withers
Feb 01, 2019
OBJECTIVE: Sympathetic nervous system and immune cell interactions play key roles in the regulation of metabolism. For example, recent convergent studies have shown that macrophages regulate obesity through brown adipose tissue...