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Chlamydia Uses K + Electrical Signalling to Orchestrate Host Sensing, Inter-Bacterial Communication and Differentiation
Prokaryotic communities coordinate quorum behaviour in response to external stimuli to control fundamental processes including inter-bacterial communication. The obligate intracellular bacterial pathogen Chlamydia adopts two...
Chlamydia exploits filopodial capture and a macropinocytosis-like pathway for host cell entry.
Pathogens hijack host endocytic pathways to force their own entry into eukaryotic target cells. Many bacteria either exploit receptor-mediated zippering or inject virulence proteins directly to trigger membrane reorganisation...
Chlamydia Uses K+ Electrical Signalling to Orchestrate Host Sensing, Inter-Bacterial Communication and Differentiation.
Prokaryotic communities coordinate quorum behaviour in response to external stimuli to control fundamental processes including inter-bacterial communication. The obligate intracellular bacterial pathogen Chlamydia adopts two...
IRE1α mediates PKR activation in response to Chlamydia trachomatis infection.
Steve J Webster, Lou Ellis, Louise M O'Brien, Beatrice Tyrrell, Timothy J Fitzmaurice, Matthew J Elder, Simon Clare, Ronnie Chee, JS Hill Gaston, Jane C Goodall
May 03, 2018
Protein kinase RNA activated (PKR) is a crucial mediator of anti-viral responses but is reported to be activated by multiple non-viral stimuli. However, mechanisms underlying PKR activation, particularly in response to bacterial...
Denoising inferred functional association networks obtained by gene fusion analysis.
Atanas Kamburov, Leon Goldovsky, Shiri Freilich, Aliki Kapazoglou, Victor Kunin, Anton J Enright, Athanasios Tsaftaris, Christos A Ouzounis
Jan 22, 2018
BACKGROUND: Gene fusion detection - also known as the 'Rosetta Stone' method - involves the identification of fused composite genes in a set of reference genomes, which indicates potential interactions between its un-fused...