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Results: 5
Unmasking herd protection by an oral cholera vaccine in a cluster-randomized trial.
Mohammad Ali, Firdausi Qadri, Deok Ryun Kim, Taufiqul Islam, Justin Im, Faisal Ahmmed, Yun Chon, Ashraful Islam Khan, Khalequ Zaman, Florian Marks, John D Clemens
Apr 18, 2019
BACKGROUND: Several studies have shown that inactivated, whole-cell oral cholera vaccines (OCVs) confer both direct protection on vaccinees and herd protection on populations. Because our earlier cluster-randomized effectiveness...
Cholera cluster-randomized trial fried-egg design vaccine effectiveness Administration Oral Adolescent Adult Aged Bangladesh Child Child Preschool Cholera Cholera Vaccines Cluster Analysis Female Humans Immunity Herd Infant Male Middle Aged Poverty Areas Proportional Hazards Models Treatment Outcome Urban Population Vaccination vaccines Inactivated Young Adult
Are better existing WASH practices in urban slums associated with a lower long-term risk of severe cholera? A prospective cohort study with 4 years of follow-up in Mirpur, Bangladesh.
Sophie Kang, Fahima Chowdhury, Juyeon Park, Tasnuva Ahmed, Birkneh Tilahun Tadesse, Md Taufiqul Islam, Deok Ryun Kim, Justin Im, Asma Binte Aziz, Masuma Hoque, Gideok Pak, Farhana Khanam, Faisal Ahmmed, Xinxue Liu, K Zaman, Ashraful Islam Khan, Jerome H Kim, Florian Marks, Firdausi Qadri, John D Clemens
Oct 24, 2022
OBJECTIVE: To investigate the association between existing household water quality, sanitation and hygiene (WASH) practices and severe cholera risk in a dense urban slum where cholera is highly endemic. DESIGN, SETTING AND...
Use of oral cholera vaccine as a vaccine probe to determine the burden of culture-negative cholera.
Justin Im, Md Taufiqul Islam, Faisal Ahmmed, Deok Ryun Kim, Yun Chon, K Zaman, Ashraful Islam Khan, Mohammad Ali, Florian Marks, Firdausi Qadri, John D Clemens
Apr 18, 2019
Analyses of stool from patients with acute watery diarrhea (AWD) using sensitive molecular diagnostics have challenged whether fecal microbiological cultures have acceptably high sensitivity for cholera diagnosis. If true, these...
Use of oral cholera vaccine as a vaccine probe to define the geographical dimensions of person-to-person transmission of cholera.
Mohammad Ali, Deok Ryun Kim, Suman Kanungo, Dipika Sur, Byomkesh Manna, Laura Digilio, Shanta Dutta, Florian Marks, Sujit K Bhattacharya, John Clemens
Feb 19, 2019
BACKGROUND: Cholera is known to be transmitted from person to person, and inactivated oral cholera vaccines (OCVs) have been shown to confer herd protection via interruption of this transmission. However, the geographic...
Efficacy of a bivalent killed whole-cell cholera vaccine over five years
Youyi Fong, M Elizabeth Halloran, Jin Kyung Park, Florian Marks, John D Clemens, Dennis L Chao
Nov 12, 2018
BACKGROUND: Oral cholera vaccine (OCV) is a feasible tool to prevent or mitigate cholera outbreaks. A better understanding of the vaccine's efficacy among different age groups and how rapidly its protection wanes could help...