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Liquid Extraction Surface Analysis (LESA) Electron-Induced Dissociation and Collision-Induced Dissociation Mass Spectrometry of Small Molecule Drug Compounds.
Andrea F Lopez-Clavijo
,
Rian L Griffiths
,
Richard JA Goodwin
,
Helen J Cooper
Jun 27, 2019
Here, we present liquid extraction surface analysis (LESA) coupled with electron-induced dissociation (EID) mass spectrometry in a Fourier-transform ion cyclotron resonance mass spectrometer for the analysis of small organic...
CID
Collision-induced dissociation
Drug compounds
EI
EID
Electron ionisation
Electron-induced dissociation
LESA
Liquid extraction surface analysis
Small molecules dissociation
Animals
Kidney
Liquid-Liquid Extraction
Male
Pharmaceutical Preparations
Pharmacokinetics
Rats
Rats
Wistar
Surface Properties
Tandem Mass Spectrometry
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