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Results: 7
A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies.
Olivia JS Macleod, Jean-Mathieu Bart, Paula MacGregor, Lori Peacock, Nicholas J Savill, Svenja Hester, Sophie Ravel, Jack D Sunter, Camilla Trevor, Steven Rust, Tristan J Vaughan, Ralph Minter, Shabaz Mohammed, Wendy Gibson, Martin C Taylor, Matthew K Higgins, Mark Carrington
Feb 19, 2020
Evaluation of Host Serum Protein Biomarkers of Tuberculosis in sub-Saharan Africa.
Thomas C Morris, Clive J Hoggart, Novel N Chegou, Martin Kidd, Tolu Oni, Rene Goliath, Katalin A Wilkinson, Hazel M Dockrell, Lifted Sichali, Louis Banda, Amelia C Crampin, Neil French, Gerhard Walzl, Michael Levin, Robert J Wilkinson, Melissa S Hamilton
May 17, 2021
Accurate and affordable point-of-care diagnostics for tuberculosis (TB) are needed. Host serum protein signatures have been derived for use in primary care settings, however validation of these in secondary care settings is...
Recurrence of complement factor H-related protein 5 nephropathy in a renal transplant.
KA Vernon, DP Gale, E Goicoechea de Jorge, AG McLean, J Galliford, A Pierides, PH Maxwell, D Taube, MC Pickering, HT Cook
Oct 31, 2019
Complement factor H-related protein 5 (CFHR5) nephropathy is a familial renal disease endemic in Cyprus. It is characterized by persistent microscopic hematuria, synpharyngitic macroscopic hematuria and progressive renal...
Inflammatory biomarkers in Alzheimer's disease plasma.
Angharad R Morgan, Samuel Touchard, Claire Leckey, Caroline O'Hagan, Alejo J Nevado-Holgado, NIMA Consortium, Frederik Barkhof, Lars Bertram, Olivier Blin, Isabelle Bos, Valerija Dobricic, Sebastiaan Engelborghs, Giovanni Frisoni, Lutz Frölich, Silvey Gabel, Peter Johannsen, Petronella Kettunen, Iwona Kłoszewska, Cristina Legido-Quigley, Alberto Lleó, Pablo Martinez-Lage, Patrizia Mecocci, Karen Meersmans, José Luis Molinuevo, Gwendoline Peyratout, Julius Popp, Jill Richardson, Isabel Sala, Philip Scheltens, Johannes Streffer, Hikka Soininen, Mikel Tainta-Cuezva, Charlotte Teunissen, Magda Tsolaki, Rik Vandenberghe, Pieter Jelle Visser, Stephanie Vos, Lars-Olof Wahlund, Anders Wallin, Sarah Westwood, Henrik Zetterberg, Simon Lovestone, B Paul Morgan, Annex: NIMA–Wellcome Trust Consortium for Neuroimmunology of Mood Disorders and Alzheimer's Disease
Jul 23, 2019
INTRODUCTION: Plasma biomarkers for Alzheimer's disease (AD) diagnosis/stratification are a "Holy Grail" of AD research and intensively sought; however, there are no well-established plasma markers. METHODS: A hypothesis-led...
Levels of soluble complement regulators predict severity of COVID-19 symptoms.
Anna L Tierney, Wajd Mohammed Alali, Thomas Scott, Karen S Rees-Unwin, CITIID-NIHR BioResource COVID-19 Collaboration, Simon J Clark, Richard D Unwin
Nov 01, 2022
Complotype affects the extent of down-regulation by Factor I of the C3b feedback cycle in vitro.
E Lay, S Nutland, JE Smith, I Hiles, RAG Smith, DJ Seilly, A Buchberger, W Schwaeble, PJ Lachmann
Oct 09, 2014
Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration.
Valentina Cipriani, Laura Lorés-Motta, Fan He, Dina Fathalla, Viranga Tilakaratna, Selina McHarg, Nadhim Bayatti, İlhan E Acar, Carel B Hoyng, Sascha Fauser, Anthony T Moore, John RW Yates, Eiko K de Jong, B Paul Morgan, Anneke I den Hollander, Paul N Bishop, Simon J Clark
Feb 06, 2021
Aged Apolipoproteins Capillaries Case-Control Studies Complement Activation Complement Factor H Genetic Predisposition to Disease Genome-Wide Association Study Haplotypes Humans Intracellular Signaling Peptides and Proteins LIM Domain Proteins Liver Macular degeneration Muscle Proteins Polymorphism Single Nucleotide Retina