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BIOSAFETY. Safeguarding gene drive experiments in the laboratory.
Omar S Akbari, Hugo J Bellen, Ethan Bier, Simon L Bullock, Austin Burt, George M Church, Kevin R Cook, Peter Duchek, Owain R Edwards, Kevin M Esvelt, Valentino M Gantz, Kent G Golic, Scott J Gratz, Melissa M Harrison, Keith R Hayes, Anthony A James, Thomas C Kaufman, Juergen Knoblich, Harmit S Malik, Kathy A Matthews, Kate M O'Connor-Giles, Annette L Parks, Norbert Perrimon, Fillip Port, Steven Russell, Ryu Ueda, Jill Wildonger
Sep 16, 2015
Building biosecurity for synthetic biology.
Benjamin D Trump, SE Galaitsi, Evan Appleton, Diederik A Bleijs, Marie-Valentine Florin, Jimmy D Gollihar, R Alexander Hamilton, Todd Kuiken, Filippa Lentzos, Ruth Mampuys, Myriam Merad, Tatyana Novossiolova, Kenneth Oye, Edward Perkins, Natàlia Garcia-Reyero, Catherine Rhodes, Igor Linkov
Aug 11, 2020
The fast-paced field of synthetic biology is fundamentally changing the global biosecurity framework. Current biosecurity regulations and strategies are based on previous governance paradigms for pathogen-oriented security...
Heat inactivation of clinical COVID-19 samples on an industrial scale for low risk and efficient high-throughput qRT-PCR diagnostic testing.
Oona Delpuech, Julie A Douthwaite, Thomas Hill, Dhevahi Niranjan, Nancy T Malintan, Hannah Duvoisin, Jane Elliott, Ian Goodfellow, Myra Hosmillo, Alexandra L Orton, Molly A Taylor, Christopher Brankin, Haidee Pitt, Douglas Ross-Thriepland, Magdalena Siek, Anna Cuthbert, Ian Richards, John R Ferdinand, Colin Barker, Robert Shaw, Cristina Ariani, Ian Waddell, Steve Rees, Clive Green, Roger Clark, Abhishek Upadhyay, Rob Howes
Feb 21, 2022
We report the development of a large scale process for heat inactivation of clinical COVID-19 samples prior to laboratory processing for detection of SARS-CoV-2 by RT-qPCR. With more than 266 million confirmed cases, over 5.26...