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Results: 5
Cover Image for Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits View Article
Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits
Genevieve M. Sullivan, Andrew K. Knutsen, Luca Peruzzotti-Jametti, Alexandru Korotcov, Asamoah Bosomtwi, Bernard J. Dardzinski, Joshua D. Bernstock, Sandra Rizzi, Frank Edenhofer, Stefano Pluchino, Regina C. Armstrong
Jun 10, 2020
Abstract: Multiple Sclerosis (MS) causes neurologic disability due to inflammation, demyelination, and neurodegeneration. Immunosuppressive treatments can modify the disease course but do not effectively promote remyelination or...
Research Neural Stem Cells remyelination Cuprizone Multiple Sclerosis Stem cell therapeutics Diffusion tensor imaging Magnetization transfer ratio Magnetic Resonance Imaging reprogramming
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Cover Image for Oligodendrocyte death and myelin loss in the cuprizone model View Article
Oligodendrocyte death and myelin loss in the cuprizone model
Martin Zirngibl, Peggy Assinck, Anastasia Sizov, Andrew V Caprariello, Jason R Plemel
May 09, 2022
Astrocytes CNS Cell Death Cuprizone Demyelination Inflammation Microglia Multiple Sclerosis Oligodendrocytes Animals Astrocytes Cuprizone Demyelinating Diseases Disease Models Animal Mice Mice Inbred C57BL Microglia Myelin Sheath Oligodendroglia
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Cover Image for Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits View Article
Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits
Genevieve M. Sullivan, Andrew K. Knutsen, Luca Peruzzotti-Jametti, Alexandru Korotcov, Asamoah Bosomtwi, Bernard J. Dardzinski, Joshua D. Bernstock, Sandra Rizzi, Frank Edenhofer, Stefano Pluchino, Regina C. Armstrong
Jun 09, 2021
Abstract: Multiple Sclerosis (MS) causes neurologic disability due to inflammation, demyelination, and neurodegeneration. Immunosuppressive treatments can modify the disease course but do not effectively promote remyelination or...
Research Neural Stem Cells remyelination Cuprizone Multiple Sclerosis Stem cell therapeutics Diffusion tensor imaging Magnetization transfer ratio Magnetic Resonance Imaging reprogramming
Published by:
Cover Image for Toxin-Based Models to Investigate Demyelination and Remyelination. View Article
Toxin-Based Models to Investigate Demyelination and Remyelination.
Christopher E McMurran, Chao Zhao, Robin Jm Franklin
Mar 14, 2019
Clinical myelin diseases, and our best experimental approximations, are complex entities in which demyelination and remyelination proceed unpredictably and concurrently. These features can make it difficult to identify...
Animal models Cuprizone Demyelination Ethidium bromide Lysolecithin Lysophosphatidylcholine remyelination Toxin Animals Cuprizone Demyelinating Diseases Disease Models Animal Ethidium Lysophosphatidylcholines Mice Mice Inbred C57BL Rats remyelination
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Cover Image for Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits. View Article
Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits.
Genevieve M Sullivan, Andrew K Knutsen, Luca Peruzzotti-Jametti, Alexandru Korotcov, Asamoah Bosomtwi, Bernard J Dardzinski, Joshua D Bernstock, Sandra Rizzi, Frank Edenhofer, Stefano Pluchino, Regina C Armstrong
Jun 17, 2020
Multiple Sclerosis (MS) causes neurologic disability due to inflammation, demyelination, and neurodegeneration. Immunosuppressive treatments can modify the disease course but do not effectively promote remyelination or prevent...
Cuprizone Diffusion tensor imaging Magnetic Resonance Imaging Magnetization transfer ratio Multiple Sclerosis Neural Stem Cells remyelination reprogramming Stem cell therapeutics
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