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Results: 5
Cytokine absorption during human kidney perfusion reduces delayed graft function-associated inflammatory gene signature.
John R Ferdinand, Sarah A Hosgood, Tom Moore, Ashley Ferro, Christopher J Ward, Tomas Castro-Dopico, Michael L Nicholson, Menna R Clatworthy
Nov 13, 2020
Transplantation is the optimal treatment for most patients with end-stage kidney disease but organ shortage is a major challenge. Normothermic machine perfusion (NMP) has been used to recondition marginal organs; however...
clinical research / practice delayed graft function (DGF) donors and donation: deceased kidney (allograft) function / dysfunction kidney disease: immune / inflammatory kidney transplantation / nephrology organ perfusion and preservation translational research / science Cytokines Delayed Graft Function Graft Survival Humans Kidney Kidney Transplantation Organ Preservation Perfusion Tissue Donors
Use of Ex Vivo Normothermic Perfusion for Quality Assessment of Discarded Human Donor Pancreases.
AD Barlow, MO Hamed, DH Mallon, RJ Brais, FM Gribble, MA Scott, WJ Howat, JA Bradley, EM Bolton, GJ Pettigrew, SA Hosgood, ML Nicholson, K Saeb-Parsy
May 19, 2015
Ischaemia reperfusion injury (IRI) organ perfusion and preservation Adolescent Adult Amylases Clinical Decision-Making Delayed Graft Function Donor Selection Female Follow-Up Studies Graft Survival Humans Male Middle Aged Organ Preservation Outcome Assessment Health Care Pancreas Transplantation Perfusion Temperature Tissue and Organ Harvesting
A pilot study evaluating GSK1070806 inhibition of interleukin-18 in renal transplant delayed graft function.
E Wlodek, RB Kirkpatrick, S Andrews, R Noble, R Schroyer, J Scott, CJE Watson, M Clatworthy, EM Harrison, SJ Wigmore, K Stevenson, D Kingsmore, NS Sheerin, O Bestard, HA Stirnadel-Farrant, L Abberley, M Busz, S DeWall, M Birchler, D Krull, KS Thorneloe, A Weber, L Devey
Apr 15, 2021
INTRODUCTION: Delayed graft function (DGF) following renal transplantation is a manifestation of acute kidney injury (AKI) leading to poor long-term outcome. Current treatments have limited effectiveness in preventing DGF....
Protocol of a randomised controlled, open-label trial of ex vivo normothermic perfusion versus static cold storage in donation after circulatory death renal transplantation.
TRANSPLANT SURGERY Adolescent Adult Aged Cold Temperature Cryopreservation Delayed Graft Function Fibrosis Graft Rejection Humans Immunosuppressive Agents Kidney Kidney Transplantation Length of Stay Middle Aged Organ Preservation Organ Preservation Solutions Perfusion Renal Dialysis Treatment Outcome Young Adult
In situ normothermic perfusion of livers in controlled circulatory death donation may prevent ischemic cholangiopathy and improve graft survival.
Christopher JE Watson, Fiona Hunt, Simon Messer, Ian Currie, Stephen Large, Andrew Sutherland, Keziah Crick, Stephen J Wigmore, Corrina Fear, Sorina Cornateanu, Lucy V Randle, John D Terrace, Sara Upponi, Rhiannon Taylor, Elisa Allen, Andrew J Butler, Gabriel C Oniscu
Jan 08, 2019
clinical research/practice donors and donation: donation after circulatory death (DCD) extracorporeal membrane oxygenation (ECMO) liver transplantation/hepatology surgical technique Adolescent Adult Aged Bile Duct Diseases Bile Ducts Child DEATH Delayed Graft Function Extracorporeal Circulation Female Graft Survival Humans Ischemia Liver Transplantation Male Middle Aged Organ Preservation Perfusion Retrospective Studies Temperature Tissue and Organ Harvesting Tissue and Organ Procurement Young Adult