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Results: 205
Radiomics of computed tomography and magnetic resonance imaging in renal cell carcinoma-a systematic review and meta-analysis.
Stephan Ursprung, Lucian Beer, Annemarie Bruining, Ramona Woitek, Grant D Stewart, Ferdia A Gallagher, Evis Sala
Jan 08, 2020
Multicentric breast cancer with heterogeneous histopathology
Giovanni Corso, Francesca Magnoni, Elena Provenzano, Antonia Girardi, Monica Iorfida, Alessandra Margherita De Scalzi, Alessandra Invento, Marco Colleoni, Enrico Cassano, Chiara Trentin, Roberto Lo Gullo, Gabriella Pravettoni, Laura Gilardi, Chiara Maria Grana, Mattia Intra, Viviana Galimberti, Paolo Veronesi, Francesca De Lorenzi, Maria Cristina Leonardi
Feb 26, 2020
Multiple synchronous (multifocal or multicentric) ipsilateral breast cancers with heterogeneous histopathology are a rare clinical occurrence, however, their incidence is increasing due to the use of MRI for breast cancer...
Breast Cancer breast cancer histotypes Diagnosis lobular carcinoma multicentric cancer Multidisciplinary team multifocal cancer Prognosis surgical management Breast Neoplasms Combined Modality Therapy Disease Management Disease Susceptibility Female Genetic Predisposition to Disease Humans Lymphoscintigraphy Multimodal Imaging Neoplasm Grading Neoplasm Staging Prognosis Retreatment Sentinel Lymph Node Biopsy Treatment Outcome Tumor Burden
Quantitative Multiparametric Breast Ultrasound
Panagiotis Kapetas, Paola Clauser, Ramona Woitek, Georg J Wengert, Mathias Lazar, Katja Pinker, Thomas H Helbich, Pascal AT Baltzer
Sep 10, 2019
OBJECTIVES: The aim of this study was to evaluate breast multiparametric ultrasound (mpUS) and its potential to reduce unnecessary breast biopsies with 1, 2, or 3 additional quantitative parameters (Doppler, elastography, and...
Adolescent Adult Aged Aged 80 and over Breast Breast Neoplasms Contrast Media Diagnosis Differential Elasticity Imaging Techniques Evaluation Studies as Topic Female Humans Image Enhancement Middle Aged Prospective Studies ROC Curve Reproducibility of Results Sensitivity and Specificity Ultrasonography Mammary Young Adult
Virtual Touch IQ elastography reduces unnecessary breast biopsies by applying quantitative "rule-in" and "rule-out" threshold values.
Panagiotis Kapetas, Paola Clauser, Ramona Woitek, Katja Pinker, Maria Bernathova, Thomas H Helbich, Pascal A Baltzer
Dec 20, 2018
Our purpose was to evaluate Virtual Touch IQ (VTIQ) elastography and identify quantitative "rule-in" and "rule-out" thresholds for the probability of malignancy, which can help avoid unnecessary breast biopsies. 189 patients...
Academic Medical Centers Austria Biopsy Breast Breast Neoplasms Cross-Sectional Studies Data Accuracy Diagnosis Differential Elasticity Imaging Techniques Feasibility Studies Female Follow-Up Studies Humans ROC Curve Retrospective Studies Sensitivity and Specificity statistics Nonparametric Ultrasonography Mammary
Molecular basis of infantile reversible cytochrome c oxidase deficiency myopathy.
Rita Horvath, John P Kemp, Helen AL Tuppen, Gavin Hudson, Anders Oldfors, Suely KN Marie, Ali-Reza Moslemi, Serenella Servidei, Elisabeth Holme, Sara Shanske, Gittan Kollberg, Parul Jayakar, Angela Pyle, Harold M Marks, Elke Holinski-Feder, Mena Scavina, Maggie C Walter, Jorida Coku, Andrea Günther-Scholz, Paul M Smith, Robert McFarland, Zofia MA Chrzanowska-Lightowlers, Robert N Lightowlers, Michio Hirano, Hanns Lochmüller, Robert W Taylor, Patrick F Chinnery, Mar Tulinius, Salvatore DiMauro
Mar 07, 2019
Childhood-onset mitochondrial encephalomyopathies are usually severe, relentlessly progressive conditions that have a fatal outcome. However, a puzzling infantile disorder, long known as 'benign cytochrome c oxidase deficiency...
Allocentric and Egocentric Spatial Processing in Middle-Aged Adults at High Risk of Late-Onset Alzheimer's Disease
Karen Ritchie, Isabelle Carrière, David Howett, Li Su, Michael Hornberger, John T O'Brien, Craig W Ritchie, Dennis Chan
Nov 12, 2018
Impairments in spatial processing due to hippocampal degeneration have been observed in the years immediately preceding the diagnosis of Alzheimer's disease (AD) dementia. The demonstration of changes in spatial processing in...
Alzheimer’s disease Cognition Diagnosis Magnetic Resonance Imaging neuropsychology Preclinical Prognosis Spatial Memory Age of Onset Alzheimer Disease Brain Cross-Sectional Studies Female Genetic Predisposition to Disease Humans Male Middle Aged Neuropsychological Tests Parents Prospective Studies Risk Factors Self Concept Space Perception Spatial Navigation
Against the stream
SummaryThe Prime Minister's challenge on dementia called for improved dementia diagnosis rates, based on assumptions of benefit to individuals and those who care for them. Subsequent policies have led to increased target drives...
Time trends in autism diagnosis over 20 years
Ginny Russell, Sal Stapley, Tamsin Newlove-Delgado, Andrew Salmon, Rhianna White, Fiona Warren, Anita Pearson, Tamsin Ford
Aug 26, 2021
BACKGROUND: Autism spectrum disorder is a diagnosis that is increasingly applied; however, previous studies have conflicting findings whether rates of diagnosis rates continue to grow in the UK. This study tested whether the...
Clinical application of autologous technetium-99m-labelled eosinophils to detect focal eosinophilic inflammation in the lung.
Chrystalla Loutsios, Neda Farahi, Rosalind Simmonds, Ian Cullum, Daniel Gillett, Chandra Solanki, Kishor Solanki, John Buscombe, Alison M Condliffe, A Mike Peters, Edwin R Chilvers
Nov 19, 2015
Expanding the definition of addiction
Addiction Behavioral addiction classification Diagnosis Impulsivity Behavior Addictive Compulsive Behavior Diagnostic and Statistical Manual of Mental Disorders Disruptive Impulse Control and Conduct Disorders Gambling Humans Impulsive Behavior International Classification of Diseases Internet Sexual Behavior
DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome.
Kate Joanne Howell, Judith Kraiczy, Komal M Nayak, Marco Gasparetto, Alexander Ross, Claire Lee, Tim N Mak, Bon-Kyoung Koo, Nitin Kumar, Trevor Lawley, Anupam Sinha, Philip Rosenstiel, Robert Heuschkel, Oliver Stegle, Matthias Zilbauer
Jan 24, 2018
BACKGROUND & AIMS: We analyzed DNA methylation patterns and transcriptomes of primary intestinal epithelial cells (IEC) of children newly diagnosed with inflammatory bowel diseases (IBD) to learn more about pathogenesis....
epigenetics Gut microbiota Human Intestinal Organoids Intestinal Epithelium Adolescent Age Factors Biopsy Case-Control Studies Colitis Ulcerative Colon Sigmoid Crohn Disease DNA Methylation Diagnosis Differential England Epigenesis Genetic Epithelial Cells Female Gastrointestinal Microbiome Gene Expression Profiling Genome-Wide Association Study Humans Ileum Intestinal Mucosa Male Organoids Predictive Value of Tests Prognosis Prospective Studies Ribotyping Time Factors Tissue Culture Techniques Transcription Genetic Transcriptome
Profiling for primary-care presentation, investigation and referral for liver cancers
BACKGROUND AND AIM: The incidence of liver cancer across Europe is increasing. There is a lack of evidence within the current literature on the identification and investigation of liver cancer within primary care. We aimed to...
Liquid Extraction Surface Analysis Mass Spectrometry Method for Identifying the Presence and Severity of Nonalcoholic Fatty Liver Disease
Guidelines for Diagnosing and Quantifying Noise-Induced Hearing Loss
This paper makes recommendations for the diagnosis and quantification of noise-induced hearing loss (NIHL) in a medico-legal context. A distinction is made between NIHL produced by: steady broadband noise, as occurs in some...
Nanotechnology-based electrochemical biosensors for monitoring breast cancer biomarkers
Hassan Nasrollahpour, Balal Khalilzadeh, Mohammad Hasanzadeh, Reza Rahbarghazi, Pedro Estrela, Abdolhossein Naseri, Savas Tasoglu, Mika Sillanpää
May 01, 2023
Breast cancer is categorized as the most widespread cancer type among women globally. On-time diagnosis can decrease the mortality rate by making the right decision in the therapy procedure. These features lead to a reduction in...
advanced nanomaterials Breast Cancer Diagnosis Electrochemistry Nanotechnology /dk/atira/pure/subjectarea/asjc/1300/1313 name=Molecular Medicine /dk/atira/pure/subjectarea/asjc/3000/3004 name=Pharmacology /dk/atira/pure/subjectarea/asjc/3000/3002 name=Drug Discovery /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Remote visualization of large-scale genomic alignments for collaborative clinical research and diagnosis of rare diseases.
Alberto Corvò, Leslie Matalonga, Dylan Spalding, Alexander Senf, Steven Laurie, Daniel Picó-Amador, Marcos Fernandez-Callejo, Ida Paramonov, Anna Foix Romero, Emilio Garcia-Rios, Jorge Izquierdo Ciges, Anand Mohan, Coline Thomas, Andres Felipe Silva Valencia, Csaba Halmagyi, Mallory Ann Freeberg, Ana Töpf, Rita Horvath, Gary Saunders, Ivo Gut, Thomas Keane, Davide Piscia, Sergi Beltran
Mar 26, 2023
The Solve-RD project objectives include solving undiagnosed rare diseases (RD) through collaborative research on shared genome-phenome datasets. The RD-Connect Genome-Phenome Analysis Platform (GPAP), for data collation and...
genome analysis Diagnosis Data sharing standards Data visualization Rare Diseases Exome Analysis Federated Infrastructures Remote Data Access
Published by: Cell genomics
Advances in Eustachian tube function testing.
Obstructive and patulous Eustachian tube dysfunction provide a significant diagnostic and management challenge. The development of new treatments such as balloon Eustachian tuboplasty has generated renewed interest in measuring...
Perforated and bleeding peptic ulcer
Antonio Tarasconi, Federico Coccolini, Walter L Biffl, Matteo Tomasoni, Luca Ansaloni, Edoardo Picetti, Sarah Molfino, Vishal Shelat, Stefania Cimbanassi, Dieter G Weber, Fikri M Abu-Zidan, Fabio C Campanile, Salomone Di Saverio, Gian Luca Baiocchi, Claudio Casella, Michael D Kelly, Andrew W Kirkpatrick, Ari Leppaniemi, Ernest E Moore, Andrew Peitzman, Gustavo Pereira Fraga, Marco Ceresoli, Ronald V Maier, Imtaz Wani, Vittoria Pattonieri, Gennaro Perrone, George Velmahos, Michael Sugrue, Massimo Sartelli, Yoram Kluger, Fausto Catena
Jan 06, 2021
BACKGROUND: Peptic ulcer disease is common with a lifetime prevalence in the general population of 5-10% and an incidence of 0.1-0.3% per year. Despite a sharp reduction in incidence and rates of hospital admission and mortality...
Angiography Antibiotics Diagnosis Embolization Guidelines High-risk patients Intra-abdominal infection non-operative management Pancreatitis Peptic ulcer Peritonitis SURGERY Technique timing Adult Combined Modality Therapy Evidence-Based Medicine Humans Peptic Ulcer Hemorrhage Peptic Ulcer Perforation
Pediatric Leukemia: Diagnosis to Treatment-A Review
Samantha C Bernard, Ehab H Abdelsamad, Paisley A Johnson, Daniel L Chapman, Madhukiran Parvathaneni
Jan 01, 0001
Leukemia is cancer of the blood and bone marrow, it is the most common cancer found in children and is found to be more than one fourth of pediatric cancers. It causes white blood cells to become abnormal and the body to become...
Pediatric leukemia Diagnosis Treatment bone marrow cancer Analytical, Diagnostic and Therapeutic Techniques and Equipment Medical Molecular Biology Medical Pharmacology Molecular, Cellular, and Tissue Engineering Pharmacy and Pharmaceutical Sciences
Published by: Harrisburg University of Science and Technology
Modern imaging of pituitary adenomas.
Waiel A Bashari, Russell Senanayake, Antía Fernández-Pombo, Daniel Gillett, Olympia Koulouri, Andrew S Powlson, Tomasz Matys, Daniel Scoffings, Heok Cheow, Iosif Mendichovszky, Mark Gurnell
Aug 21, 2019
Negative Predictive Value of Multiparametric Magnetic Resonance Imaging in the Detection of Clinically Significant Prostate Cancer in the Prostate Imaging Reporting and Data System Era
Niranjan J Sathianathen, Altan Omer, Eli Harriss, Lucy Davies, Veeru Kasivisvanathan, Shonit Punwani, Caroline M Moore, Christof Kastner, Tristan Barrett, Roderick Cn Van Den Bergh, Ben A Eddy, Fergus Gleeson, Ruth Macpherson, Richard J Bryant, James WF Catto, Declan G Murphy, Freddie C Hamdy, Hashim U Ahmed, Alastair D Lamb
May 26, 2020
CONTEXT: Prebiopsy multiparametric magnetic resonance imaging (mpMRI) is increasingly used in prostate cancer diagnosis. The reported negative predictive value (NPV) of mpMRI is used by some clinicians to aid in decision making...
Diagnosing cancer in primary care
Ruth Swann, Sean McPhail, Jana Witt, Brian Shand, Gary A Abel, Sara Hiom, Jem Rashbass, Georgios Lyratzopoulos, Greg Rubin, National Cancer Diagnosis Audit Steering Group
Mar 07, 2018
BACKGROUND: Continual improvements in diagnostic processes are needed to minimise the proportion of patients with cancer who experience diagnostic delays. Clinical audit is a means of achieving this. AIM: To characterise key...
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