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Results: 37
Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease.
Lisa Mayr, Felix Grabherr, Julian Schwärzler, Isabelle Reitmeier, Felix Sommer, Thomas Gehmacher, Lukas Niederreiter, Gui-Wei He, Barbara Ruder, Kai TR Kunz, Piotr Tymoszuk, Richard Hilbe, David Haschka, Clemens Feistritzer, Romana R Gerner, Barbara Enrich, Nicole Przysiecki, Markus Seifert, Markus A Keller, Georg Oberhuber, Susanne Sprung, Qitao Ran, Robert Koch, Maria Effenberger, Ivan Tancevski, Heinz Zoller, Alexander R Moschen, Günter Weiss, Christoph Becker, Philip Rosenstiel, Arthur Kaser, Herbert Tilg, Timon E Adolph
Apr 08, 2020
The increased incidence of inflammatory bowel disease (IBD) has become a global phenomenon that could be related to adoption of a Western life-style. Westernization of dietary habits is partly characterized by enrichment with...
Quality of dietary fat and genetic risk of type 2 diabetes
Jordi Merino, Marta Guasch-Ferré, Christina Ellervik, Hassan S Dashti, Stephen J Sharp, Peitao Wu, Kim Overvad, Chloé Sarnowski, Mikko Kuokkanen, Rozenn N Lemaitre, Anne E Justice, Ulrika Ericson, Kim VE Braun, Yuvaraj Mahendran, Alexis C Frazier-Wood, Dianjianyi Sun, Audrey Y Chu, Toshiko Tanaka, Jian'an Luan, Jaeyoung Hong, Anne Tjønneland, Ming Ding, Annamari Lundqvist, Kenneth Mukamal, Rebecca Rohde, Christina-Alexandra Schulz, Oscar H Franco, Niels Grarup, Yii-Der Ida Chen, Lydia Bazzano, Paul W Franks, Julie E Buring, Claudia Langenberg, Ching-Ti Liu, Torben Hansen, Majken K Jensen, Katri Sääksjärvi, Bruce M Psaty, Kristin L Young, George Hindy, Camilla Helene Sandholt, Paul M Ridker, Jose M Ordovas, James B Meigs, Oluf Pedersen, Peter Kraft, Markus Perola, Kari E North, Marju Orho-Melander, Trudy Voortman, Ulla Toft, Jerome I Rotter, Lu Qi, Nita G Forouhi, Dariush Mozaffarian, Thorkild IA Sørensen, Meir J Stampfer, Satu Männistö, Elizabeth Selvin, Fumiaki Imamura, Veikko Salomaa, Frank B Hu, Nick J Wareham, Josée Dupuis, Caren E Smith, Tuomas O Kilpeläinen, Daniel I Chasman, Jose C Florez
Aug 07, 2019
The Dietary Total-Fat Content Affects the In Vivo Circulating C15:0 and C17
Benjamin Jenkins, Manar Aoun, Christine Feillet-Coudray, Charles Coudray, Martin Ronis, Albert Koulman
Dec 10, 2018
Pentadecanoic acid (C15:0) and heptadecanoic acid (C17:0) have been described as dietary biomarkers of dairy-fat consumption, with varying degrees of reliability between studies. It remains unclear how the total amount of...
The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children
Aino-Maija Eloranta, Taisa Sallinen, Anna Viitasalo, Niina Lintu, Juuso Väistö, Henna Jalkanen, Tuomo T Tompuri, Sonja Soininen, Eero A Haapala, Sanna Kiiskinen, Theresia M Schnurr, Tuomas O Kilpeläinen, Santtu Mikkonen, Kai Savonen, Mustafa Atalay, Soren Brage, David E Laaksonen, Virpi Lindi, Jyrki Ågren, Ursula Schwab, Jarmo Jääskeläinen, Timo A Lakka
Jun 01, 2020
PURPOSE: We studied the effects of a physical activity and dietary intervention on plasma lipids in a general population of children. We also investigated how lifestyle changes contributed to the intervention effects. METHODS...
Cross-sectional study of diet patterns in early and chronic schizophrenia.
Linda Scoriels, Jorge Zimbron, Nuria Garcia-León, Montse Coll-Negre, Maria Giro, Jesus Perez, Peter B Jones, Emilio Fernandez-Egea
Apr 05, 2019
Letter to the Editor
One of the most complex comorbidities to treat in schizophrenia is obesity and overweight. This multifactorial condition is estimated to affect over 60% of the patients and is linked to a shorter lifespan....
Association between enteral macronutrient delivery and inflammatory response in critically ill children.
Sara Zaher, Deborah White, Jenna Ridout, Frederic Valla, Ricardo Branco, Rosan Meyer, Nazima Pathan
Dec 04, 2018
Critical Illness Cytokines Enteral feeding Macronutrients Malnutrition Underfeeding Adolescent Child Child Preschool Critical Illness Cytokines Dietary Carbohydrates Dietary Fats Enteral nutrition Humans Infant Infant Newborn Inflammation nutrients Prospective Studies Respiration Artificial Treatment Outcome
Adherence to predefined dietary patterns and incident type 2 diabetes in European populations
InterAct Consortium
Jan 23, 2018
AIMS/HYPOTHESIS: Few studies have investigated the relationship between predefined dietary patterns and type 2 diabetes incidence; little is known about the generalisability of these associations. We aimed to assess the...
Adult Aged Beverages Carbonated Beverages Case-Control Studies dairy products Diabetes mellitus Type 2 Diet Diet Surveys Dietary Fats Dietary Proteins Energy Intake Europe Feeding Behavior Female Fruit Health Knowledge Attitudes practice Humans Incidence Male Middle Aged Prospective Studies Risk Factors Risk Reduction Behavior Surveys and Questionnaires Sweetening Agents Vegetables White People
Shotgun Lipidomics Discovered Diurnal Regulation of Lipid Metabolism Linked to Insulin Sensitivity in Nondiabetic Men.
Katharina Kessler, Mathias J Gerl, Silke Hornemann, Markus Damm, Christian Klose, Klaus J Petzke, Margrit Kemper, Daniela Weber, Natalia Rudovich, Tilman Grune, Kai Simons, Achim Kramer, Andreas FH Pfeiffer, Olga Pivovarova-Ramich
Nov 22, 2019
CONTEXT: Meal timing affects metabolic homeostasis and body weight, but how composition and timing of meals affect plasma lipidomics in humans is not well studied. OBJECTIVE: We used high throughput shotgun plasma lipidomics to...
circadian clock glucose metabolism insulin sensitivity Lipid Metabolism meal timing plasma lipidome Adult Blood Glucose Carbohydrate Metabolism Circadian Rhythm Cross-Over Studies Diet High-Fat Dietary Carbohydrates Dietary Fats Germany Humans Insulin Insulin Resistance Lipid Metabolism lipidomics Male Meals Middle Aged Postprandial Period
Changes of Dietary Fat and Carbohydrate Content Alter Central and Peripheral Clock in Humans.
Olga Pivovarova, Karsten Jürchott, Natalia Rudovich, Silke Hornemann, Lu Ye, Simona Möckel, Veronica Murahovschi, Katharina Kessler, Anne-Cathrin Seltmann, Christiane Maser-Gluth, Jeannine Mazuch, Michael Kruse, Andreas Busjahn, Achim Kramer, Andreas FH Pfeiffer
Aug 01, 2019
CONTEXT: The circadian clock coordinates numerous metabolic processes with light-dark and feeding regimens. However, in humans it is unknown whether dietary patterns influence circadian rhythms. OBJECTIVE: We examined the...
An AGTR1 Variant Worsens Nonalcoholic Fatty Liver Disease and the Metabolic Syndrome
Nonalcoholic fatty liver disease and hypertension are closely related but there has been little genetic evidence to link them. In this issue, Musso et al. provide evidence that a common variant in AGTR1 (A1166C) is associated...
Changes in household food and drink purchases following restrictions on the advertisement of high fat, salt, and sugar products across the Transport for London network
Amy Yau, Nicolas Berger, Cherry Law, Laura Cornelsen, Robert Greener, Jean Adams, Emma J Boyland, Thomas Burgoine, Frank De Vocht, Matt Egan, Vanessa Er, Amelia A Lake, Karen Lock, Oliver Mytton, Mark Petticrew, Claire Thompson, Martin White, Steven Cummins
Mar 20, 2022
Describing a new food group classification system for UK biobank
Carmen Piernas, Aurora Perez-Cornago, Min Gao, Heather Young, Zoe Pollard, Angela Mulligan, Marleen Lentjes, Jennifer Carter, Kathryn Bradbury, Tim J Key, Susan A Jebb
Nov 25, 2021
PURPOSE: The UK Biobank study collected detailed dietary data using a web-based self-administered 24 h assessment tool, the Oxford WebQ. We aimed to describe a comprehensive food grouping system for this questionnaire and to...
Suppression of enteroendocrine cell glucagon-like peptide (GLP)-1 release by fat-induced small intestinal ketogenesis
Ville Wallenius, Erik Elias, Erik Elebring, Bauke Haisma, Anna Casselbrant, Pierre Larraufie, Emma Spak, Frank Reimann, Carel W le Roux, Neil G Docherty, Fiona M Gribble, Lars Fändriks
Nov 13, 2019
Diabetes mellitus enterocyte biology glucagen-like peptides obesity surgery small bowel 3-Hydroxybutyric Acid Anastomosis Roux-en-Y Animals Caloric Restriction Cells Cultured Dietary Fats Emulsions Enteroendocrine Cells Fat Emulsions Intravenous Female Gastric Bypass Glucagon-Like Peptide 1 Humans Hydroxymethylglutaryl-CoA Synthase Intestinal Mucosa Jejunum ketone bodies Ketones Liver Male Mice Mice Inbred C57BL Middle Aged Phospholipids Postoperative Period Preoperative Period Primary Cell Culture Soybean Oil
Novel ketone diet enhances physical and cognitive performance.
Andrew J Murray, Nicholas S Knight, Mark A Cole, Lowri E Cochlin, Emma Carter, Kirill Tchabanenko, Tica Pichulik, Melanie K Gulston, Helen J Atherton, Marie A Schroeder, Robert MJ Deacon, Yoshihiro Kashiwaya, M Todd King, Robert Pawlosky, J Nicholas P Rawlins, Damian J Tyler, Julian L Griffin, Jeremy Robertson, Richard L Veech, Kieran Clarke
Sep 29, 2016
Surplus fat rapidly increases fat oxidation and insulin resistance in lipodystrophic mice.
Amandine Girousse, Samuel Virtue, Dan Hart, Antonio Vidal-Puig, Peter R Murgatroyd, Etienne Mouisel, Coralie Sengenès, David B Savage
Sep 05, 2018
OBJECTIVE: Surplus dietary fat cannot be converted into other macronutrient forms or excreted, so has to be stored or oxidized. Healthy mammals store excess energy in the form of triacylgycerol (TAG) in lipid droplets within...
Energy partitioning fatty acid oxidation Insulin Resistance lipodystrophy Substrate competition Adipocytes Adipose Tissue Adiposity Animals Diet High-Fat Dietary Fats Energy Intake Energy Metabolism Fatty Liver Glucose Hyperinsulinism Insulin Resistance Lipids lipodystrophy Liver Mice obesity Oxidation-Reduction Weight Gain
Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes
Fumiaki Imamura, Amanda Fretts, Matti Marklund, Andres V Ardisson Korat, Wei-Sin Yang, Maria Lankinen, Waqas Qureshi, Catherine Helmer, Tzu-An Chen, Kerry Wong, Julie K Bassett, Rachel Murphy, Nathan Tintle, Chaoyu Ian Yu, Ingeborg A Brouwer, Kuo-Liong Chien, Alexis C Frazier-Wood, Liana C Del Gobbo, Luc Djoussé, Johanna M Geleijnse, Graham G Giles, Janette de Goede, Vilmundur Gudnason, William S Harris, Allison Hodge, Frank Hu, InterAct Consortium, Albert Koulman, Markku Laakso, Lars Lind, Hung-Ju Lin, Barbara McKnight, Kalina Rajaobelina, Ulf Risérus, Jennifer G Robinson, Cécilia Samieri, David S Siscovick, Sabita S Soedamah-Muthu, Nona Sotoodehnia, Qi Sun, Michael Y Tsai, Matti Uusitupa, Lynne E Wagenknecht, Nick J Wareham, Jason HY Wu, Renata Micha, Nita G Forouhi, Rozenn N Lemaitre, Dariush Mozaffarian, Fatty Acids and Outcomes Research Consortium (FORCE)
Nov 16, 2018
BACKGROUND: We aimed to investigate prospective associations of circulating or adipose tissue odd-chain fatty acids 15:0 and 17:0 and trans-palmitoleic acid, t16:1n-7, as potential biomarkers of dairy fat intake, with incident...
A Meta-Analysis of Food Labeling Effects on Consumer Diet Behaviors and Industry Practices.
Siyi Shangguan, Ashkan Afshin, Masha Shulkin, Wenjie Ma, Daniel Marsden, Jessica Smith, Michael Saheb-Kashaf, Peilin Shi, Renata Micha, Fumiaki Imamura, Dariush Mozaffarian, Food PRICE (Policy Review and Intervention Cost-Effectiveness) Project
Jan 07, 2019
CONTEXT: The influence of food and beverage labeling (food labeling) on consumer behaviors, industry responses, and health outcomes is not well established. EVIDENCE ACQUISITION: PRISMA (Preferred Reporting Items for Systematic...
Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet.
Adiponectin Animals Blood Glucose Caloric Restriction Delta-5 Fatty Acid Desaturase Diet High-Fat Dietary Fats Docosahexaenoic Acids Eicosapentaenoic Acid Fatty Acid Desaturases Insulin Leptin Linoleic Acid Lipogenesis Liver Male obesity Rats Rats Sprague-Dawley Stearoyl-CoA Desaturase Subcutaneous Fat Triglycerides Weight Gain alpha-Linolenic Acid
Divergent effects of central melanocortin signalling on fat and sucrose preference in humans.
Agatha A van der Klaauw, Julia M Keogh, Elana Henning, Cheryl Stephenson, Sarah Kelway, Victoria M Trowse, Naresh Subramanian, Stephen O'Rahilly, Paul C Fletcher, I Sadaf Farooqi
Oct 03, 2016
Neural correlates of fat preference in frontotemporal dementia
Rebekah M Ahmed, Nga Yan Tse, Yu Chen, Elana Henning, John R Hodges, Matthew C Kiernan, Muireann Irish, I Sadaf Farooqi, Olivier Piguet
May 11, 2021
Metabolomics applied to diabetes-lessons from human population studies.
The 'classical' distribution of type 2 diabetes (T2D) across the globe is rapidly changing and it is no longer predominantly a disease of middle-aged/elderly adults of western countries, but it is becoming more common through...
Predictors of change in objectively measured and self-reported health behaviours among individuals with recently diagnosed type 2 diabetes
Laura Kuznetsov, Rebecca K Simmons, Stephen Sutton, Ann-Louise Kinmonth, Simon J Griffin, Wendy Hardeman, ADDITION-Plus study team
Jun 13, 2018
BACKGROUND: There is limited evidence about predictors of health behaviour change in people with type 2 diabetes. The aim of this study was to assess change in health behaviours over one year and to identify predictors of...
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