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Cover Image for A novel complexity-to-diversity strategy for the diversity-oriented synthesis of structurally diverse and complex macrocycles from quinine.

A novel complexity-to-diversity strategy for the diversity-oriented synthesis of structurally diverse and complex macrocycles from quinine.

JJ Ciardiello, HL Stewart, HF Sore, WRJD Galloway, DR Spring

Feb 28, 2017

Chemical space Complexity-to-diversity Diversity-oriented synthesis Library synthesis macrocycles natural products Scaffold Macrocyclic Compounds Molecular Structure Quinine

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Cover Image for A Multidimensional Diversity-Oriented Synthesis Strategy for Structurally Diverse and Complex Macrocycles

A Multidimensional Diversity-Oriented Synthesis Strategy for Structurally Diverse and Complex Macrocycles

F Nie, DL Kunciw, D Wilcke, JE Stokes, WRJD Galloway, S Bartlett, HF Sore, DR Spring

Feb 16, 2017

Diversity-oriented synthesis macrocycles molecular diversity synthesis design synthetic methods

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Cover Image for Recent Applications of Diversity-Oriented Synthesis Toward Novel, 3-Dimensional Fragment Collections.

Recent Applications of Diversity-Oriented Synthesis Toward Novel, 3-Dimensional Fragment Collections.

Sarah L Kidd, Thomas J Osberger, Natalia Mateu, Hannah F Sore, David R Spring

Nov 23, 2018

compound collections Diversity-oriented synthesis Fragment-based drug discovery medicinal chemistry organic synthesis

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Cover Image for Synthesis of Structurally Diverse N-Substituted Quaternary-Carbon-Containing Small Molecules from α,α-Disubstituted Propargyl Amino Esters.

Synthesis of Structurally Diverse N-Substituted Quaternary-Carbon-Containing Small Molecules from α,α-Disubstituted Propargyl Amino Esters.

Natalia Mateu, Sarah L Kidd, Leen Kalash, Hannah F Sore, Andrew Madin, Andreas Bender, David R Spring

Sep 05, 2018

Diversity-oriented synthesis Drug Discovery medicinal chemistry molecular diversity quaternary stereocenters

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Cover Image for An expedient strategy for the diversity-oriented synthesis of macrocyclic compounds with natural product-like characteristics

An expedient strategy for the diversity-oriented synthesis of macrocyclic compounds with natural product-like characteristics

JJ Ciardiello, WRJD Galloway, CJ O'Connor, HF Sore, JE Stokes, Y Wu, DR Spring

Oct 22, 2015

macrocycles Diversity-oriented synthesis Scaffold Chemical space

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