Search

BACKGROUND: Smart materials capable of responding to external stimuli are noteworthy candidates in designing drug delivery systems. In many of the recent research, temperature and pH have been recognized as the main stimulating...

DOX PVCL Raft Cancer Drug delivery Lysine Caprolactam Cell Death Doxorubicin Drug Carriers Drug Delivery Systems Drug Liberation Humans Hydrogels Hydrogen-Ion Concentration Lysine MCF-7 Cells Molecular Weight Nanoparticles Phase Transition Polymers Proton Magnetic Resonance Spectroscopy spectroscopy Fourier Transform Infrared Temperature Toxicity Tests

In the last decade significant advances have been made in process analytical technologies and digital manufacturing of pharmaceutical oral solid dosage forms leading to enhanced product knowledge and process understanding. These...

Models process analytical technology Real-time release testing soft sensors Tablet manufacturing Drug Compounding Drug Liberation Kinetics Pharmaceutical Preparations Quality Control Tablets technology Pharmaceutical Workflow

Microbubbles and microcapsules of silane-polycaprolactone (SiPCL) have been filled with a fluorescent acridium salt (lucigenin) as a model for a drug-loaded delivery vehicle. The uptake and delivery were studied and compared...

Capsules Drug Delivery Systems Drug Liberation Silicon Dioxide Solubility

Less is more: The efficacy of antibody-drug conjugates (ADCs) for cancer therapy is traditionally associated with cleavable linkers for payload release. Evidence now suggests that simpler constructs without cleavable moieties...

anti-tumor agents antibody-drug conjugates bioconjugation Drug delivery linkers Animals Breast Neoplasms Bystander Effect Cell Line Tumor Drug Liberation Female Humans Immunoconjugates Mice Neoplasms Oligopeptides Transplantation Heterologous

Colloidosomes have attracted considerable attention in recent years because of their potential applications in a range of industries, such as food, bioreactors and medicine. However, traditional polymer shell colloidosomes leak...

Animals Cell Line Tumor Cell Survival Colloids Doxorubicin Drug Carriers Drug Liberation gold Rats Solvents Temperature Ultrasonic Waves

The fabrication, characterization, and therapy efficiency of a noncovalent-bonded hydrogel network, which is assembled by utilizing cucurbit[7]uril as a supramolecular linker to "stick" superparamagnetic γ-Fe2 O3 nanoparticles...

cucurbit[7]uril drug release Hydrogels supramolecular chemistry thermotherapy Animals Antibiotics Antineoplastic Bridged-Ring Compounds Catechols Chitosan Cross-Linking Reagents Doxorubicin Drug Liberation HeLa Cells Humans Hydrogels hyperthermia Induced Imidazoles Magnetic Phenomena Magnetic Resonance Spectroscopy Magnetite Nanoparticles Mice Nude Xenograft Model Antitumor Assays

Amides Animals Antineoplastic Agents Cell Line Tumor Cell Proliferation cisplatin Drug Liberation Drug Screening Assays Antitumor Humans Molecular Structure Morphinans Neoplasms Experimental Platinum Zebrafish

Nanotechnology-based antitumor drug delivery systems, known as nanocarriers, have demonstrated their efficacy in recent years. Typically, the size of the nanocarriers is around 100 nm. It is imperative to achieve an optimum size...

endogenous pH-responsive nanocarriers size change Targeted drug delivery tumor therapy Antineoplastic Agents Drug Carriers Drug Delivery Systems Drug Liberation Endosomes Hydrogen-Ion Concentration Lysosomes Nanoparticles Nanotechnology Neoplasms Particle Size

Antineoplastic Agents Drug Delivery Systems Drug Liberation HeLa Cells Humans metal-organic frameworks Microscopy Electron Scanning Porosity Temperature zirconium

Chemistry Pharmaceutical Dosage Forms Drug Compounding Drug Liberation excipients Humans Pharmaceutical Preparations Solubility

Drug Delivery Systems in vitro models oral drug delivery Pediatric physical characterization Breast Feeding Drug Delivery Systems Drug Liberation Equipment Design Humans Infant Peristalsis Pharmaceutical Preparations Rhodamines Tablets Tongue

3D printing X-ray computed microtomography (XμCT) MICROSTRUCTURE polyvinyl alcohol (PVA) terahertz pulsed imaging (TPI) Chemistry Pharmaceutical Computer-Aided Design Dosage Forms Drug Delivery Systems Drug Liberation Pharmaceutical Preparations Phenanthrenes Polyesters Polyvinyl Alcohol Porosity printing printing Three-Dimensional technology Pharmaceutical Terahertz Imaging X-Ray Microtomography X-Rays

Cell Survival Doxorubicin Drug Carriers Drug Liberation HeLa Cells Humans metal-organic frameworks Molecular Dynamics Simulation Nanoparticles Phosphates Polyethylene Glycols