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Animals Cocaine Conditioning Operant Drug-Seeking Behavior Male Models Neurological Prefrontal Cortex Rats Receptors Dopamine D1 Receptors Dopamine D2 Receptors Serotonin 5-HT2 Reversal Learning Reward Ventral Striatum

Addiction Alcohol Compulsivity Dopamine seeking Striatum Alcoholism Animals Compulsive Behavior Corpus Striatum Dopamine Dopamine Antagonists Drug-Seeking Behavior Flupenthixol Male Rats Reward

The transition from recreational drug use to compulsive drug-seeking habits, the hallmark of addiction, has been shown to depend on a shift in the locus of control over behaviour from the ventral to the dorsolateral striatum....

Addiction Astrocytes Dopamine Glutamate Habits Relapse Striatum tripartite synapse Animals Astrocytes Corpus Striatum Dopamine Drug-Seeking Behavior Homeostasis Humans Nucleus Accumbens Substance-Related Disorders

Excessive drinking is an important behavioural characteristic of alcohol addiction, but not the only one. Individuals addicted to alcohol crave alcoholic beverages, spend time seeking alcohol despite negative consequences and...

Alcohol Compulsivity Contingency degradation devaluation Quinine seeking Alcohol Drinking Alcoholism Animals Compulsive Behavior Conditioning Operant Corpus Striatum Drug-Seeking Behavior Habits learning Male Rats Self Administration

Behavioral models Cocaine Compulsive drug seeking Limbic System Substance use disorders Animals Behavior Addictive Disease Models Animal Drug-Seeking Behavior Humans Substance-Related Disorders

The alarming increase in heroin overdoses in the USA is a reminder of the need for efficacious and novel treatments for opiate addiction. This may reflect the relatively poor understanding of the neural basis of heroin, as...

Astrocytes Dopamine Glutamate Habits Heroin Acetylcysteine Animals Behavior Animal Cocaine Dopamine Dopamine Antagonists Dopamine Uptake Inhibitors Drug-Seeking Behavior Heroin Male Reinforcement psychology Self Administration

Alcohol Deterrents Alcohol Drinking Alcohol-Related Disorders Animals Blood Alcohol Content Choice Behavior Conditioning Operant Cues Disease Models Animal Dose-Response Relationship Drug Drug Evaluation Preclinical Drug-Seeking Behavior Indans Male Naltrexone Narcotic Antagonists Rats Receptors Opioid mu Reinforcement psychology Species Specificity Triazoles

Adrenergic Agonists Adrenergic beta-Antagonists Animals Conditioning Classical Cues Drug-Seeking Behavior Epinephrine Ethanol Male Memory Consolidation Nadolol Propranolol Rats Receptors Adrenergic beta Reinforcement psychology Self Administration

Animals Basolateral Nuclear Complex Behavior Animal Central Amygdaloid Nucleus Cocaine Drug-Seeking Behavior Excitatory Amino Acid Antagonists Isoxazoles Male N-Methylaspartate Rats Rats Sprague-Dawley Receptors glutamate Self Administration Tetrazoles

Animals Cocaine Cocaine-Related Disorders Conditioning Operant Drug-Seeking Behavior Male motivation Punishment Rats Reinforcement psychology Self Administration Sucrose

basolateral amygdala Chemogenetics Cocaine Conditioned reinforcement Nucleus accumbens core Second-order schedule of reinforcement Animals Basolateral Nuclear Complex Cocaine Cues Drug-Seeking Behavior Nucleus Accumbens Rats Rats Sprague-Dawley Self Administration

Cocaine goal-directed behavior Incentive habits Negative urgency Relapse Striatum Animals Cocaine Cocaine-Related Disorders Cues Drug-Seeking Behavior Male Rats Rats Sprague-Dawley Recurrence Self Administration

Endophenotype inhibitory control Insula Prefrontal Cortex Striatum vulnerability Animals Brain Compulsive Behavior Conditioning (Psychology) Drug-Seeking Behavior Habits Humans Substance-Related Disorders

Alcohol Drinking Animals Compulsive Behavior Drug-Seeking Behavior Ethanol Indans Male Phenotype Rats Receptors Opioid mu Time Factors Triazoles