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The RNA-binding protein HuR is essential for the B cell antibody response.
Manuel D Diaz-Muñoz, Sarah E Bell, Kirsten Fairfax, Elisa Monzon-Casanova, Adam F Cunningham, Mar Gonzalez-Porta, Simon R Andrews, Victoria I Bunik, Kathi Zarnack, Tomaž Curk, Ward A Heggermont, Stephane Heymans, Gary E Gibson, Dimitris L Kontoyiannis, Jernej Ule, Martin Turner
Jun 24, 2019
Post-transcriptional regulation of mRNA by the RNA-binding protein HuR (encoded by Elavl1) is required in B cells for the germinal center reaction and for the production of class-switched antibodies in response to...
Acyltransferases Alternative Splicing Animals Antigens B-Lymphocytes Cell Death Cell Differentiation Cell Proliferation ELAV Proteins Erythrocytes Germinal Center Immunity Humoral Immunization Immunoglobulin Class Switching Immunoglobulins Lipopolysaccharides Mice Mice Inbred C57BL Mice Knockout Mitochondria RNA Messenger Reactive Oxygen Species Sheep