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Early pre-radiographic structural pathology precedes the onset of accelerated knee osteoarthritis.
Matthew S Harkey, Julie E Davis, Bing Lu, Lori Lyn Price, Robert J Ward, James W Mackay, Charles B Eaton, Grace H Lo, Mary F Barbe, Ming Zhang, Jincheng Pang, Alina C Stout, Timothy E McAlindon, Jeffrey B Driban
Aug 22, 2019
BACKGROUND: Accelerated knee osteoarthritis (AKOA) is characterized by more pain, impaired physical function, and greater likelihood to receive a joint replacement compared to individuals who develop the typical gradual onset of...
Bone marrow lesion Cartilage Effusion-synovitis Extensor mechanism ligament MRI meniscus Tendons Aged Anterior Cruciate Ligament Disease Progression Female Humans Longitudinal Studies Magnetic Resonance Imaging Male Menisci Tibial Middle Aged Osteoarthritis Knee Posterior Cruciate Ligament Prognosis Risk Factors Synovitis Time Factors