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Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development.

Magdalena K Sznurkowska, Edouard Hannezo, Roberta Azzarelli, Steffen Rulands, Sonia Nestorowa, Christopher J Hindley, Jennifer Nichols, Berthold Göttgens, Meritxell Huch, Anna Philpott, Benjamin D Simons

Sep 20, 2018

acini branching morphogenesis development DIFFERENTIATION ducts islets Pancreas specification tubulogenesis Acinar Cells Animals Cell Differentiation Cell Lineage Cell Proliferation Endocrine Cells Gene Expression Regulation Developmental Morphogenesis Organogenesis Pancreas Stem Cells

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Cover Image for MYC functions are specific in biological subtypes of breast cancer and confers resistance to endocrine therapy in luminal tumours.

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MYC functions are specific in biological subtypes of breast cancer and confers resistance to endocrine therapy in luminal tumours.

Andrew R Green, Mohammed A Aleskandarany, Devika Agarwal, Somaia Elsheikh, Christopher C Nolan, Maria Diez-Rodriguez, R Douglas Macmillan, Graham R Ball, Carlos Caldas, Srinivasan Madhusudan, Ian O Ellis, Emad A Rakha

Jan 11, 2018

BACKGROUND: MYC is amplified in approximately 15% of breast cancers (BCs) and is associated with poor outcome. c-MYC protein is multi-faceted and participates in many aspects of cellular function and is linked with therapeutic...

Aged Ataxia Telangiectasia Mutated Proteins Biomarkers Tumor Breast Neoplasms Class I Phosphatidylinositol 3-Kinases Cyclin B1 Cyclin E Disease-Free Survival Drug Resistance Neoplasm Endocrine Cells Female Gene Expression Profiling Gene Expression Regulation Neoplastic Humans Phosphatidylinositol 3-Kinases Prognosis Proto-Oncogene Proteins c-myc RNA Messenger Receptor ErbB-2

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