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Results: 7
Beth Blane, Hayley J Brodrick, Theodore Gouliouris, Kirsty E Ambridge, Angela D Kidney, Catherine M Ludden, Direk Limmathurotsakul, M Estée Török, Sharon J Peacock
Nov 11, 2015
Chromogenic agar detection Enterobacteriaceae Extended-spectrum β-lactamase Selectivity sensitivity Anti-Bacterial Agents Carrier State Ceftizoxime Disk Diffusion Antimicrobial Tests Enterobacteriaceae Enterobacteriaceae Infections Feces Humans Nursing Homes Sensitivity and Specificity beta-Lactamases
GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation.
Tomas Castro-Dopico, Aaron Fleming, Thomas W Dennison, John R Ferdinand, Katherine Harcourt, Benjamin J Stewart, Zaeem Cader, Zewen K Tuong, Chenzhi Jing, Laurence SC Lok, Rebeccah J Mathews, Anaïs Portet, Arthur Kaser, Simon Clare, Menna R Clatworthy
Jun 16, 2020
Macrophages play a central role in intestinal immunity, but inappropriate macrophage activation is associated with inflammatory bowel disease (IBD). Here, we identify granulocyte-macrophage colony stimulating factor (GM-CSF) as...
GM-CSF anti-microbial defense Crosstalk inflammatory bowel disease innate lymphoid cells MACROPHAGES Wound Healing Animals Cell Polarity Citrobacter rodentium Colitis Enterobacteriaceae Infections Granulocyte-Macrophage Colony-Stimulating Factor Humans Immunity Innate Inflammation Intestines Lymphocytes Macrophage Activation MACROPHAGES Mice Inbred C57BL Phenotype Wound Healing
Extended-spectrum β-lactamase-producing and carbapenemase-producing Enterobacteriaceae.
CPE ESBL Enterobacteriaceae Gram-negative Antimicrobial resistance Anti-Bacterial Agents Antimicrobial Stewardship Bacterial Proteins Carbapenem-Resistant Enterobacteriaceae Drug Resistance Multiple Bacterial Enterobacteriaceae Enterobacteriaceae Infections Genes Bacterial Humans molecular epidemiology prevalence whole genome sequencing beta-Lactamases
Citrobacter rodentium is an unstable pathogen showing evidence of significant genomic flux.
Nicola K Petty, Theresa Feltwell, Derek Pickard, Simon Clare, Ana L Toribio, Maria Fookes, Kevin Roberts, Rita Monson, Satheesh Nair, Robert A Kingsley, Richard Bulgin, Siouxsie Wiles, David Goulding, Thomas Keane, Craig Corton, Nicola Lennard, David Harris, David Willey, Richard Rance, Lu Yu, Jyoti S Choudhary, Carol Churcher, Michael A Quail, Julian Parkhill, Gad Frankel, Gordon Dougan, George PC Salmond, Nicholas R Thomson
Jan 14, 2020
Citrobacter rodentium is a natural mouse pathogen that causes attaching and effacing (A/E) lesions. It shares a common virulence strategy with the clinically significant human A/E pathogens enteropathogenic E. coli (EPEC) and...
Animals Citrobacter rodentium DNA Bacterial Disease Models Animal Electrophoresis Gel Pulsed-Field Enterobacteriaceae Infections Female Gene Expression Profiling Gene Rearrangement Genome Bacterial Genomic Instability Humans Interspersed Repetitive Sequences Mice Mice Inbred C57BL Plasmids Prophages Sequence Analysis DNA Virulence
Colonisation with ESBL-producing and carbapenemase-producing Enterobacteriaceae, vancomycin-resistant enterococci, and meticillin-resistant Staphylococcus aureus in a long-term care facility over one year.
Catherine Ludden, Martin Cormican, Akke Vellinga, James R Johnson, Bernie Austin, Dearbháile Morris
Sep 29, 2016
BACKGROUND: This study examined colonisation with and characteristics of antimicrobial-resistant organisms among residents of a long-term care facility (LTCF) over one year, including strain persistence and molecular diversity...
Aged Aged 80 and over Bacterial Proteins Carrier State Electrophoresis Gel Pulsed-Field Enterobacteriaceae Enterobacteriaceae Infections Escherichia coli Escherichia coli Infections Female Gram-Negative Bacterial Infections Gram-Positive Bacterial Infections Humans Klebsiella Infections Klebsiella pneumoniae Long-Term Care Male Methicillin Methicillin-Resistant Staphylococcus aureus molecular epidemiology Nursing Homes Polymerase Chain Reaction Staphylococcal Infections Vancomycin-Resistant Enterococci beta-Lactamases
The global distribution and spread of the mobilized colistin resistance gene mcr-1.
Ruobing Wang, Lucy van Dorp, Liam P Shaw, Phelim Bradley, Qi Wang, Xiaojuan Wang, Longyang Jin, Qing Zhang, Yuqing Liu, Adrien Rieux, Thamarai Dorai-Schneiders, Lucy Anne Weinert, Zamin Iqbal, Xavier Didelot, Hui Wang, Francois Balloux
Sep 10, 2018
Colistin represents one of the few available drugs for treating infections caused by carbapenem-resistant Enterobacteriaceae. As such, the recent plasmid-mediated spread of the colistin resistance gene mcr-1 poses a significant...
Americas Anti-Bacterial Agents Asia Carbapenems Colistin DNA Transposable Elements Drug Resistance Multiple Bacterial Enterobacteriaceae Enterobacteriaceae Infections Escherichia coli Proteins Europe evolution Molecular Gene Expression Gene Transfer Horizontal Genome Bacterial Humans Plasmids Population Dynamics
Point-prevalence survey of carbapenemase-producing Enterobacteriaceae and vancomycin-resistant enterococci in adult inpatients in a university teaching hospital in the UK.
Infections with carbapenemase-producing Enterobacteriaceae (CPE) and vancomycin-resistant enterococci (VRE) are associated with increased morbidity and mortality, but the carriage rates of CRE and VRE among hospital inpatients...
CPE carriage prevalence SURVEILLANCE VRE Adolescent Adult Aged Aged 80 and over Carbapenem-Resistant Enterobacteriaceae Carrier State Enterobacteriaceae Infections Female Gram-Positive Bacterial Infections Hospitals University Humans Inpatients Male Middle Aged prevalence Surveys and Questionnaires United Kingdom Vancomycin-Resistant Enterococci Young Adult