Determining Risk of Barrett's Esophagus and Esophageal Adenocarcinoma Based on Epidemiologic Factors and Genetic Variants.
Jing Dong,
Matthew F Buas,
Puya Gharahkhani,
Bradley J Kendall,
Lynn Onstad,
Shanshan Zhao,
Lesley A Anderson,
Anna H Wu,
Weimin Ye,
Nigel C Bird,
Leslie Bernstein,
Wong-Ho Chow,
Marilie D Gammon,
Geoffrey Liu,
Carlos Caldas,
Paul D Pharoah,
Harvey A Risch,
Prasad G Iyer,
Brian J Reid,
Laura J Hardie,
Jesper Lagergren,
Nicholas J Shaheen,
Douglas A Corley,
Rebecca C Fitzgerald,
Stomach and Oesophageal Cancer Study (SOCS) consortium,
David C Whiteman,
Thomas L Vaughan,
Aaron P Thrift
Feb 23, 2018
BACKGROUND & AIMS: We developed comprehensive models to determine risk of Barrett's esophagus (BE) or esophageal adenocarcinoma (EAC) based on genetic and non-genetic factors. METHODS: We used pooled data from 3288 patients with...