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Results: 21
Correcting for optimistic prediction in small data sets.
The C statistic is a commonly reported measure of screening test performance. Optimistic estimation of the C statistic is a frequent problem because of overfitting of statistical models in small data sets, and methods exist to...
Estimating the number of people with hepatitis C virus who have ever injected drugs and have yet to be diagnosed
Teresa C Prevost, Anne M Presanis, Avril Taylor, David J Goldberg, Sharon J Hutchinson, Daniela De Angelis
Jul 11, 2018
AIMS: To estimate the number of people who have ever injected drugs (defined here as PWID) living in Scotland in 2009 who have been infected with the hepatitis C virus (HCV) and to quantify and characterize the population...
Power, participation and their problems
Ayako Ebata, Catherine Hodge, Dorien Braam, Linda Waldman, Joanne Sharp, Hayley MacGregor, Henrietta Moore
Apr 17, 2020
The use of Participatory Epidemiology in veterinary research intends to include livestock keepers and other local stakeholders in research processes and the development of solutions to animal health problems, including...
Impact of follow-up time and analytical approaches to account for reverse causality on the association between physical activity and health outcomes in UK Biobank.
Tessa Strain, Katrien Wijndaele, Stephen J Sharp, Paddy C Dempsey, Nick Wareham, Søren Brage
Sep 18, 2019
The validity and reliability of the CAMDEX-DS for assessing dementia in adults with Down syndrome in Brazil.
Luciana M Fonseca, Glenda G Haddad, Guilherme P Mattar, Melaine C de Oliveira, Sharon S Simon, Laura M Guilhoto, Geraldo F Busatto, Shahid Zaman, Anthony J Holland, Marcelo Q Hoexter, Cassio M Bottino
Jul 06, 2020
OBJECTIVE: Alzheimer's disease occurs at a higher prevalence and an earlier age in individuals with Down syndrome (DS) than typically developing individuals. However, diagnosing dementia in individuals with intellectual...
Estimating epidemiological parameters from experiments in vector access to host plants, the method of matching gradients.
Estimation of pathogenic life-history values, for instance the duration a pathogen is retained in an insect vector (i.e., retention period) is of particular importance for understanding plant disease epidemiology. How can we...
Use of previous-day recalls of physical activity and sedentary behavior in epidemiologic studies
Charles E Matthews, David Berrigan, Beate Fischer, Sjaan R Gomersall, Andrea Hillreiner, Youngwon Kim, Michael F Leitzmann, Pedro Saint-Maurice, Timothy S Olds, Gregory J Welk
Jun 06, 2020
BACKGROUND: The last few years have seen renewed interest in use-of-time recalls in epidemiological studies, driven by a focus on the 24-h day [including sleep, sitting, and light physical activity (LPA)] rather than just...
behaviour change ecological momentary assessment energy expenditure Exposure assessment measurement Public Health sitting time Accelerometry Adult Australia Computers Energy Metabolism Epidemiologic Methods Epidemiologic Studies Exercise Female Germany Humans Male Mental Recall New Zealand Reproducibility of Results Sedentary Behavior Sex Factors Sleep Time Factors Time and Motion Studies Transportation United States
Bayesian evidence synthesis to estimate HIV prevalence in men who have sex with men in Poland at the end of 2009.
HIV spread in men who have sex with men (MSM) is an increasing problem in Poland. Despite the existence of a surveillance system, there is no direct evidence to allow estimation of HIV prevalence and the proportion undiagnosed...
The Consortium of Metabolomics Studies (COMETS)
Bing Yu, Krista A Zanetti, Marinella Temprosa, Demetrius Albanes, Nathan Appel, Clara Barrios Barrera, Yoav Ben-Shlomo, Eric Boerwinkle, Juan P Casas, Clary Clish, Caroline Dale, Abbas Dehghan, Andriy Derkach, A Heather Eliassen, Paul Elliott, Eoin Fahy, Christian Gieger, Marc J Gunter, Sei Harada, Tamara Harris, Deron R Herr, David Herrington, Joel N Hirschhorn, Elise Hoover, Ann W Hsing, Mattias Johansson, Rachel S Kelly, Chin Meng Khoo, Mika Kivimäki, Bruce S Kristal, Claudia Langenberg, Jessica Lasky-Su, Deborah A Lawlor, Luca A Lotta, Massimo Mangino, Loïc Le Marchand, Ewy Mathé, Charles E Matthews, Cristina Menni, Lorelei A Mucci, Rachel Murphy, Matej Oresic, Eric Orwoll, Jennifer Ose, Alexandre C Pereira, Mary C Playdon, Lucilla Poston, Jackie Price, Qibin Qi, Kathryn Rexrode, Adam Risch, Joshua Sampson, Wei Jie Seow, Howard D Sesso, Svati H Shah, Xiao-Ou Shu, Gordon CS Smith, Ulla Sovio, Victoria L Stevens, Rachael Stolzenberg-Solomon, Toru Takebayashi, Therese Tillin, Ruth Travis, Ioanna Tzoulaki, Cornelia M Ulrich, Ramachandran S Vasan, Mukesh Verma, Ying Wang, Nick J Wareham, Andrew Wong, Naji Younes, Hua Zhao, Wei Zheng, Steven C Moore
Feb 11, 2019
Cancer cohort Diabetes Genetics Heart Disease Metabolomics Prospective Adolescent Adult Aged Aged 80 and over Biomarkers Body Mass Index Child Epidemiologic Methods EPIDEMIOLOGY Female Global Health Health Behavior Hematologic Tests Humans Longitudinal Studies Male Metabolomics Middle Aged Prospective Studies Socioeconomic Factors Young Adult
Self-reported parkinsonian symptoms in the EPIC-Norfolk cohort
Neurodegenerative Brain Disorders Clinical Research aging Neurosciences Parkinson's Disease 2 Aetiology 2.4 Surveillance and distribution Neurological Aged Cohort Studies Cross-Sectional Studies Data Collection Diagnosis Differential Epidemiologic Methods Female Humans Male Middle Aged Parkinson Disease Population Groups prevalence Self-Assessment Severity of Illness Index Surveys and Questionnaires United Kingdom
Andrew J Atkin, Trish Gorely, Stacy A Clemes, Thomas Yates, Charlotte Edwardson, Soren Brage, Jo Salmon, Simon J Marshall, Stuart JH Biddle
Jan 22, 2016
OutbreakTools
Thibaut Jombart, David M Aanensen, Marc Baguelin, Paul Birrell, Simon Cauchemez, Anton Camacho, Caroline Colijn, Caitlin Collins, Anne Cori, Xavier Didelot, Christophe Fraser, Simon Frost, Niel Hens, Joseph Hugues, Michael Höhle, Lulla Opatowski, Andrew Rambaut, Oliver Ratmann, Samuel Soubeyrand, Marc A Suchard, Jacco Wallinga, Rolf Ypma, Neil Ferguson
Jul 17, 2018
The investigation of infectious disease outbreaks relies on the analysis of increasingly complex and diverse data, which offer new prospects for gaining insights into disease transmission processes and informing public health...
Analyses of Sensitivity to the Missing-at-Random Assumption Using Multiple Imputation With Delta Adjustment
Multiple imputation with delta adjustment provides a flexible and transparent means to impute univariate missing data under general missing-not-at-random mechanisms. This facilitates the conduct of analyses assessing sensitivity...
causal mediation analysis incomplete data nonignorable nonresponse sensitivity analysis AIDS-Related Opportunistic Infections Adolescent Adult Data Interpretation Statistical Epidemiologic Methods Female HIV Infections Humans Logistic Models Male Middle Aged Models Statistical Odds Ratio prevalence Risk Factors Tuberculosis Young Adult
Duration of untreated psychosis and clinical outcomes of first episode psychosis
Methods for observed-cluster inference when cluster size is informative
Multivariable Mendelian randomization
Mendelian randomization causal inference Epidemiologic Methods instrumental variables lipid fractions pleiotropy Biomarkers Causality Cholesterol HDL Cholesterol LDL Coronary Disease Genetic Pleiotropy genetic variation Humans Mathematical Computing Mendelian Randomization Analysis Models Genetic Predictive Value of Tests Risk Factors Sensitivity and Specificity Triglycerides United Kingdom
Estimating the prevalence of problem drug use from drug-related mortality data.
Hayley E Jones, Ross J Harris, Beatrice C Downing, Matthias Pierce, Tim Millar, AE Ades, Nicky J Welton, Anne M Presanis, Daniela De Angelis, Matthew Hickman
Aug 26, 2020
BACKGROUND AND AIMS: Indirect estimation methods are required for estimating the size of populations where only a proportion of individuals are observed directly, such as problem drug users (PDUs). Capture-recapture and...
Diagnostic importance of pulmonary interleukin-1beta and interleukin-8 in ventilator-associated pneumonia.
Andrew Conway Morris, Kallirroi Kefala, Thomas S Wilkinson, Olga Lucia Moncayo-Nieto, Kevin Dhaliwal, Lesley Farrell, Timothy S Walsh, Simon J Mackenzie, David G Swann, Peter JD Andrews, Niall Anderson, John RW Govan, Ian F Laurenson, Hamish Reid, Donald J Davidson, Christopher Haslett, Jean-Michel Sallenave, A John Simpson
Jul 02, 2020
BACKGROUND: Ventilator-associated pneumonia (VAP) is the most commonly fatal nosocomial infection. Clinical diagnosis of VAP remains notoriously inaccurate. The hypothesis was tested that significantly augmented inflammatory...
Dementia Research Fit for the Planet
Carol E Brayne, Linda E Barnes, Monique MB Breteler, Rachael L Brooks, Carole Dufouil, Chris Fox, Laura Fratiglioni, M Arfan Ikram, Rose A Kenny, Miia Kivipelto, Antonio Lobo, Massimo Musicco, Chengxuan Qiu, Edo Richard, Steffi G Riedel-Heller, Craig Ritchie, Ingmar Skoog, Blossom CM Stephan, Annalena Venneri, Fiona E Matthews
Feb 14, 2020
In recent years, a rapidly increasing collection of investigative methods in addition to changes in diagnostic criteria for dementia have followed "high-tech" trends in medicine, with the aim to better define the dementia...