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BACKGROUND: Evolutionary information contained in the amino acid sequences of proteins specifies the biological function and fold, but exactly what information contained in the protein sequence drives both of these processes?...

Computational protein design Evolutionary coupling analysis Protein Folding Protein structure prediction Amino Acid Sequence Computational Biology Computer Simulation Entropy Humans Mutation Protein Engineering Protein Folding Proteins Receptors Adrenergic beta-2 Sequence Analysis Software