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Cardiovascular disease (CVD) has been identified as a leading cause of death in the United States, with more than two million Americans having a heart attack or a stroke and close to a million deaths each year. Research shows...

Cardiovascular Exercise Intervention FITNESS HEALTH Body Mass Index blood cholesterol Blood Glucose Cardiology Cardiovascular Diseases cardiovascular system Exercise Physiology Medicine and Health Sciences

Fatty acids are an important energy source in long duration endurance exercise. From the blood, fatty acids enter cells in the skeletal muscle and enter the mitochondria to participate in metabolic pathways to regenerate...

physical activity fatty acid oxidation metabolism Exercise Physiology Medicine and Health Sciences

Cardiovascular (CV) disease is the leading cause of death in the United States. Research consistently shows that those at the highest risk for CV disease are those who are overweight and have low fitness and activity levels....

Cardiovascular Exercise Intervention vascular HEALTH short-term blood pressure Blood Glucose Cholesterol artery wall Cardiology Cardiovascular Diseases Exercise Physiology Medicine and Health Sciences

Previous studies suggest that sex differences in lipid metabolism exist with females demonstrating a higher utilization of lipids during exercise, which is mediated partly by increased utilization of muscle triglycerides....

Exercise Metabolism Exercise Physiology fatty acid oxidation Ketosis triglyceride metabolism Exercise Physiology

We will compare vascular measures and fitness levels between adults categorized with MHO or MUO. There will be sub-analysis of the vascular differences between the two cohorts in response to a four-week resistance training...

metabolically healthy obesity Body composition vascular health Cardiovascular health Exercise Resistance training Exercise Physiology Medicine and Health Sciences

Joint misalignment and reduced range of motion (ROM) can lead to discomfort during physical activity, thus creating a barrier to exercise. Lack of physical activity is related to cardiovascular (CV) disease and obesity. Studies...

joint angle Range of Motion Cardiovascular health obesity Q angle dorsiflexion Exercise Physiology Life Sciences Medicine and Health Sciences

Research has demonstrated that the high capacity requirements of the heart are satisfied by a preference for oxidation of fatty acids. However, it is well known that a stressed heart, as in pathological hypertrophy, deviates...

Exercise training Lipid Metabolism metabolic remodeling fatty acid oxidation exercise adaptation Heart Failure cardiac hypertrophy Cardiovascular Diseases Exercise Physiology Nutritional and Metabolic Diseases

The ketogenic diet (KD) is a high-fat, low-carbohydrate diet that results in the elevation of serum ketone bodies, known as ketosis. This metabolic consequence has been suggested as a method for treating neurological conditions...

Ketosis Glucose Intolerance Lipid accumulation ketone bodies metabolism Exercise Physiology

Ketone bodies have been identified as an important, alternative fuel source in heart failure. In addition, the use of ketone bodies as a fuel source has been suggested to be a potential ergogenic aid for endurance exercise...

Ischemia Reperfusion Hypoxia beta-hydroxybutyrate Ketosis Cardiovascular Diseases Exercise Physiology Medical Nutrition Medicine and Health Sciences

The promotion of ketone body (KB) metabolism via ketosis has been suggested as a strategy to increase exercise performance. However, studies in humans and animals have yielded inconsistent results. The purpose of the current...

nutritional ketosis Lipid Metabolism ketone body metabolism Glycogen Triglycerides Exercise Physiology

The purpose of this study is to examine how two four-week self-report exercise interventions modify cardiovascular health measures; including BP, blood glucose and cholesterol levels, body fat percentage, brachial artery FMD...

Cardiovascular health IMT FMD Body composition Exercise intervention Exercise Physiology Medicine and Health Sciences PREVENTIVE MEDICINE

Although exercise training is an important recommendation for the management of type 1 diabetes (T1D), most of the available research studies predominantly focus on male subjects. Given the importance of sex as a biological...

glucose metabolism streptozotocin Insulin chronic exercise hyperlipidemia Ketosis Endocrinology, Diabetes, and Metabolism Exercise Physiology