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Vascular Thrombosis in Severe COVID-19 Requiring Extracorporeal Membrane Oxygenation
Jonathan R Weir-McCall, Gabriel Galea, Sze Mun Mak, Kushal Joshi, Bobby Agrawal, Nicholas Screaton, Mark Toshner, Alessandro Ruggiero, Giulia Benedetti, Jan Brozik, Ruth Machin, Indrajeet Das, Marusa Kotnik, Julia Sun, Michael Mackay, Joseph Jacob, Jonathan CL Rodrigues, Luigi Camporota, Alain Vuylsteke
Oct 11, 2021
OBJECTIVES: Coronavirus disease 2019 has been reported to be a prothrombotic condition; however, multicenter data comparing this with other viral pneumonias in those requiring extracorporeal membrane oxygenation are lacking. We...
Pulmonary infections complicating ARDS.
Charles-Edouard Luyt, Lila Bouadma, Andrew Conway Morris, Jayesh A Dhanani, Marin Kollef, Jeffrey Lipman, Ignacio Martin-Loeches, Saad Nseir, Otavio T Ranzani, Antoine Roquilly, Matthieu Schmidt, Antoni Torres, Jean-François Timsit
Dec 02, 2020
Pulmonary infection is one of the main complications occurring in patients suffering from acute respiratory distress syndrome (ARDS). Besides traditional risk factors, dysregulation of lung immune defenses and microbiota may...
Whole-blood Point-of-Care Activated Partial Thromboplastin Time Ratio (APR) is not Accurate Enough to Monitor Heparin Therapy in Patients with Severe Respiratory Failure Secondary to SARS-Cov-2 Infection Supported with Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO).
Outcomes of the NHS England National Extracorporeal Membrane Oxygenation Service for adults with respiratory failure
Alex Warren, Yi-da Chiu, Sofía S Villar, Jo-Anne Fowles, Nicola Symes, Julian Barker, Luigi Camporota, Chris Harvey, Stephane Ledot, Ian Scott, Alain Vuylsteke, NHS England-commissioned National ECMO Service
Jul 02, 2020
BACKGROUND: Extracorporeal membrane oxygenation (ECMO) is increasingly used to support adults with severe respiratory failure refractory to conventional measures. In 2011, NHS England commissioned a national service to provide...
Cerebral Autoregulation, Cerebral Hemodynamics, and Injury Biomarkers, in Patients with COVID-19 Treated with Veno-Venous Extracorporeal Membrane Oxygenation.
Małgorzata Burzyńska, Agnieszka Uryga, Magdalena Kasprowicz, Marek Czosnyka, Waldemar Goździk, Chiara Robba
Apr 17, 2023
BACKGROUND: This study aimed to describe the cerebrovascular dynamics, in particular cerebral autoregulation (CA), and cerebral biomarkers as neuron-specific enolase (NSE) in patients with a diagnosis of coronavirus disease 2019...
Continuous Monitoring of Cerebral Autoregulation in Children Supported by Extracorporeal Membrane Oxygenation
Nicolas Joram, Erta Beqiri, Stefano Pezzato, Moscatelli Andrea, Chiara Robba, Jean-Michel Liet, Alexis Chenouard, Pierre Bourgoin, Marek Czosnyka, Pierre-Louis Léger, Peter Smielewski
Oct 15, 2020
OBJECTIVE: Cerebral autoregulation (CA) impairment may pose a risk factor for neurological complications among children supported by extracorporeal membrane oxygenation (ECMO). Our first objective was to investigate the...
Neonatal cerebrovascular autoregulation.
Christopher J Rhee, Cristine Sortica da Costa, Topun Austin, Ken M Brady, Marek Czosnyka, Jennifer K Lee
Dec 17, 2018
Cerebrovascular pressure autoregulation is the physiologic mechanism that holds cerebral blood flow (CBF) relatively constant across changes in cerebral perfusion pressure (CPP). Cerebral vasoreactivity refers to the...
Predictors of intracranial hemorrhage in adult patients on extracorporeal membrane oxygenation
Alexander Fletcher-Sandersjöö, Jiri Bartek, Eric Peter Thelin, Anders Eriksson, Adrian Elmi-Terander, Mikael Broman, Bo-Michael Bellander
Dec 04, 2017
BACKGROUND: Intracranial hemorrhage (ICH) is a recognized complication of adults treated with extracorporeal membrane oxygenation (ECMO) and is associated with increased morbidity and mortality. However, the predictors of ICH in...
Asthma, ECMO and eosinophils.
Tom McLellan, Chinmay Patvardhan, Doris Rassl, Huw Steven Jenkins, Martin Knolle, Muhunthan Thillai
Jan 29, 2021
COVID-19 and pneumothorax
Anthony W Martinelli, Tejas Ingle, Joseph Newman, Iftikhar Nadeem, Karl Jackson, Nicholas D Lane, James Melhorn, Helen E Davies, Anthony J Rostron, Aldrin Adeni, Kevin Conroy, Nick Woznitza, Matthew Matson, Simon E Brill, James Murray, Amar Shah, Revati Naran, Samanjit S Hare, Oliver Collas, Sarah Bigham, Michael Spiro, Margaret M Huang, Beenish Iqbal, Sarah Trenfield, Stephane Ledot, Sujal Desai, Lewis Standing, Judith Babar, Razeen Mahroof, Ian Smith, Kai Lee, Nairi Tchrakian, Stephanie Uys, William Ricketts, Anant RC Patel, Avinash Aujayeb, Maria Kokosi, Alexander JK Wilkinson, Stefan J Marciniak
Sep 28, 2020
INTRODUCTION: Pneumothorax and pneumomediastinum have both been noted to complicate cases of coronavirus disease 2019 (COVID-19) requiring hospital admission. We report the largest case series yet described of patients with both...