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FGFR1 amplification or overexpression and hormonal resistance in luminal breast cancer
Silvana Mouron, Luis Manso, Eduardo Caleiras, Jose L. Rodriguez-Peralto, Oscar M. Rueda, Carlos Caldas, Ramon Colomer, Miguel Quintela-Fandino, Maria J. Bueno
Feb 13, 2021
Abstract: Background: FGFR1 amplification, but not overexpression, has been related to adverse prognosis in hormone-positive breast cancer (HRPBC). Whether FGFR1 overexpression and amplification are correlated, what is their...
FGFR1 amplification or overexpression and hormonal resistance in luminal breast cancer
Silvana Mouron, Luis Manso, Eduardo Caleiras, Jose L Rodriguez-Peralto, Oscar M Rueda, Carlos Caldas, Ramon Colomer, Miguel Quintela-Fandino, Maria J Bueno
Apr 09, 2021
BACKGROUND: FGFR1 amplification, but not overexpression, has been related to adverse prognosis in hormone-positive breast cancer (HRPBC). Whether FGFR1 overexpression and amplification are correlated, what is their distribution...
FGFR1 amplification FGFR1 overexpression Luminal breast cancer palbociclib Rogaratinib Adult Aged Aged 80 and over Antineoplastic Agents Biomarkers Tumor Breast Neoplasms Cell Line Tumor Cyclin-Dependent Kinase 4 Cyclin-Dependent Kinase 6 Disease Management Disease Susceptibility Drug Resistance Multiple Drug Resistance Neoplasm Female Gene Amplification Gene Expression Humans In Situ Hybridization Fluorescence Middle Aged Molecular Targeted Therapy Neoplasm Staging Prognosis RNA Messenger Receptor Fibroblast Growth Factor Type 1 Receptors Estrogen Treatment Outcome Young Adult