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Results: 9
Thermally reduced graphene oxide nanohybrids of chiral functional naphthalenediimides for prostate cancer cells bioimaging
James A. Tyson, Vincenzo Mirabello, David G. Calatayud, Haobo Ge, Gabriele Kociok-Kohn, Stanley W. Botchway, Dan Pantos, Sofia I. Pascu
Aug 17, 2016
This study reports on the supramolecular assemblies formed between planar carbon systems (PCSs) such as thermally reduced graphene oxide (TRGO) and its small-molecule model system coronene and a series of d- and l-α amino...
Quantification of protein-protein interactions and activation dynamics
Oncogene dysregulation is a driver of neoplasia development and progression. The use of quantitative molecular imaging to quantify oncogene activation will be crucial in developing companion diagnostics which can identify...
Removing physiological motion from intravital and clinical functional imaging data.
Sean C Warren, Max Nobis, Astrid Magenau, Yousuf H Mohammed, David Herrmann, Imogen Moran, Claire Vennin, James RW Conway, Pauline Mélénec, Thomas R Cox, Yingxiao Wang, Jennifer P Morton, Heidi CE Welch, Douglas Strathdee, Kurt I Anderson, Tri Giang Phan, Michael S Roberts, Paul Timpson
Jun 27, 2019
Intravital microscopy can provide unique insights into the function of biological processes in a native context. However, physiological motion caused by peristalsis, respiration and the heartbeat can present a significant...
FLIM FRET Cell Biology Computational Biology human Intravital Microscopy motion correction MOUSE multiphoton Systems Biology Algorithms Animals Biosensing Techniques Cell Adhesion Computer Simulation Fluorescence Resonance Energy Transfer Guanosine Triphosphate Humans Imaging Three-Dimensional Intestines Intravital Microscopy Mice Microscopy Fluorescence Models Biological Motion Neoplasm Metastasis Neuropeptides Pancreatic Neoplasms Skin Software rac1 GTP-Binding Protein src-Family Kinases
A method for the fast and photon-efficient analysis of time-domain fluorescence lifetime image data over large dynamic ranges.
Fluorescence lifetime imaging (FLIM) allows the quantification of sub-cellular processes in situ, in living cells. A number of approaches have been developed to extract the lifetime from time-domain FLIM data, but they are often...
Quantification of protein-protein interactions and activation dynamics
Oncogene dysregulation is a driver of neoplasia development and progression. The use of quantitative molecular imaging to quantify oncogene activation will be crucial in developing companion diagnostics which can identify...
Thermally reduced graphene oxide nanohybrids of chiral functional naphthalenediimides for prostate cancer cells bioimaging
James A. Tyson, Vincenzo Mirabello, David G. Calatayud, Haobo Ge, Gabriele Kociok-Kohn, Stanley W. Botchway, Dan Pantos, Sofia I. Pascu
Aug 17, 2016
This study reports on the supramolecular assemblies formed between planar carbon systems (PCSs) such as thermally reduced graphene oxide (TRGO) and its small-molecule model system coronene and a series of d- and l-α amino...
Correlative FLIM-confocal-Raman mapping applied to plant lignin composition and autofluorescence.
Fluorescence lifetime imaging microscopy (FLIM) is a useful tool for discriminating fluorescent moieties, based on photon lifetimes, that cannot be otherwise resolved by looking solely at their excitation/emission...