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Maternal Metformin Intervention during Obese Glucose-Intolerant Pregnancy Affects Adiposity in Young Adult Mouse Offspring in a Sex-Specific Manner.
Josca M Schoonejans, Heather L Blackmore, Thomas J Ashmore, Catherine E Aiken, Denise S Fernandez-Twinn, Susan E Ozanne
Jul 27, 2021
BACKGROUND: Metformin is commonly used to treat gestational diabetes mellitus. This study investigated the effect of maternal metformin intervention during obese glucose-intolerant pregnancy on the gonadal white adipose tissue...
Associations of maternal and paternal antenatal mood with offspring anxiety disorder at age 18 years.
Lauren E Capron, Vivette Glover, Rebecca M Pearson, Jonathan Evans, Thomas G O'Connor, Alan Stein, Susannah E Murphy, Paul G Ramchandani
Jan 08, 2019
OBJECTIVE: Maternal antenatal depression and anxiety are associated with increased risk of childhood behavioural and emotional problems in offspring; it remains unclear to what extent this is due to a maternal biological impact...
ALSPAC Anxiety Depression Foetal programming Maternal Paternal Adolescent Adult affect Anxiety Disorders Child of Impaired Parents Cohort Studies Depressive Disorder Fathers Female Humans Interview Psychological Longitudinal Studies Male Mental Disorders Mothers Odds Ratio Pregnancy Pregnancy Complications United Kingdom
Maternal Metformin Intervention during Obese Glucose-Intolerant Pregnancy Affects Adiposity in Young Adult Mouse Offspring in a Sex-Specific Manner.
Josca M Schoonejans, Heather L Blackmore, Thomas J Ashmore, Catherine E Aiken, Denise S Fernandez-Twinn, Susan E Ozanne
Sep 08, 2021
Background
Metformin is commonly used to treat gestational diabetes mellitus. This study investigated the effect of maternal metformin intervention during obese glucose-intolerant pregnancy on the gonadal white adipose...
Metformin Sex differences Gestational diabetes White adipose tissue Maternal obesity Foetal programming
Published by: International journal of molecular sciences
Maternal Metformin Intervention during Obese Glucose-Intolerant Pregnancy Affects Adiposity in Young Adult Mouse Offspring in a Sex-Specific Manner
Josca M. Schoonejans, Heather L. Blackmore, Thomas J. Ashmore, Catherine E. Aiken, Denise S. Fernandez-Twinn, Susan E. Ozanne
Jul 29, 2021
Background: Metformin is commonly used to treat gestational diabetes mellitus. This study investigated the effect of maternal metformin intervention during obese glucose-intolerant pregnancy on the gonadal white adipose tissue...