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Cycloaddition Strategies for the Synthesis of Diverse Heterocyclic Spirocycles for Fragment-Based Drug Discovery.
Thomas A King, Hannah L Stewart, Kim T Mortensen, Andrew JP North, Hannah F Sore, David R Spring
Jul 12, 2019
In recent years the pharmaceutical industry has benefited from the advances made in fragment-based drug discovery (FBDD) with more than 30 fragment-derived drugs currently marketed or progressing through clinical trials. The...