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Cover Image for Freezing of Aqueous Solutions and Chemical Stability of Amorphous Pharmaceuticals

Freezing of Aqueous Solutions and Chemical Stability of Amorphous Pharmaceuticals

Evgenyi Shalaev, Alan Soper, J Axel Zeitler, Satoshi Ohtake, Christopher J Roberts, Michael J Pikal, Ke Wu, Elena Boldyreva

Sep 20, 2018

amorphism chemical stability deamidation freeze-drying lyophilization protein formulation(s) solid-state Stability structure water sorption Chemical Phenomena Chemistry Pharmaceutical Drug Stability Freeze Drying Freezing Hydrolysis Solutions Temperature water

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Cover Image for Cell structure, stiffness and permeability of freeze-dried collagen scaffolds in dry and hydrated states.

Cell structure, stiffness and permeability of freeze-dried collagen scaffolds in dry and hydrated states.

MC Varley, S Neelakantan, TW Clyne, J Dean, RA Brooks, AE Markaki

Feb 01, 2016

Cell interconnectivity Cell structure collagen scaffolds Specific permeability Specific surface area Young’s modulus Biomechanical Phenomena Collagen Compressive Strength Elastic Modulus Freeze Drying Glycosaminoglycans Permeability Tissue Engineering Tissue Scaffolds Tomography water

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Cover Image for Multi-scale mechanical response of freeze-dried collagen scaffolds for tissue engineering applications.

Multi-scale mechanical response of freeze-dried collagen scaffolds for tissue engineering applications.

Giovanni S Offeddu, Jennifer C Ashworth, Ruth E Cameron, Michelle L Oyen

Dec 03, 2014

Colloidal probe AFM Indentation Scaffolds mechanics Type I collagen Viscoelastic Animals Biomechanical Phenomena Cattle Collagen Type I Elasticity Freeze Drying Materials Testing Mechanical Phenomena Membranes Artificial Tissue Engineering Tissue Scaffolds Viscosity

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Cover Image for Structural determinants of hydration, mechanics and fluid flow in freeze-dried collagen scaffolds.

Cover Image for Transistor in a tube

Cover Image for A design protocol for tailoring ice-templated scaffold structure.

Cover Image for Scale and structure dependent solute diffusivity within microporous tissue engineering scaffolds.

Scale and structure dependent solute diffusivity within microporous tissue engineering scaffolds.

Giovanni S Offeddu, Lakshana Mohee, Ruth E Cameron

Apr 27, 2020

Cell microenvironment Collagen FRAP Molecular transport Porous media microstructure Animals Biocompatible Materials Collagen Freeze Drying Tissue Engineering Tissue Scaffolds

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Cover Image for Label-free single-particle imaging of the influenza virus by objective-type total internal reflection dark-field microscopy.

Label-free single-particle imaging of the influenza virus by objective-type total internal reflection dark-field microscopy.

Sawako Enoki, Ryota Iino, Nobuhiro Morone, Kunihiro Kaihatsu, Shouichi Sakakihara, Nobuo Kato, Hiroyuki Noji

May 28, 2019

Here we report label-free optical imaging of single particles of the influenza virus attached on a glass surface with a simple objective-type total internal reflection dark-field microscopy (TIRDFM). The capability of TIRDFM for...

Freeze Drying Microscopy Electron Scanning Microscopy Electron Transmission Microscopy Fluorescence Orthomyxoviridae Semiconductors

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Cover Image for Alpha-2-Macroglobulin Is Acutely Sensitive to Freezing and Lyophilization

Alpha-2-Macroglobulin Is Acutely Sensitive to Freezing and Lyophilization

Amy R Wyatt, Janet R Kumita, Natalie E Farrawell, Christopher M Dobson, Mark R Wilson

Jun 16, 2015

Freeze Drying Freezing Glucose Humans Protein Conformation Sodium Chloride Sucrose alpha-Macroglobulins

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