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GATA6 Cooperates with EOMES/SMAD2/3 to Deploy the Gene Regulatory Network Governing Human Definitive Endoderm and Pancreas Formation.
Crystal Y Chia, Pedro Madrigal, Simon LIJ Denil, Iker Martinez, Jose Garcia-Bernardo, Ranna El-Khairi, Mariya Chhatriwala, Maggie H Shepherd, Andrew T Hattersley, N Ray Dunn, Ludovic Vallier
Jan 28, 2019
GATA6 definitive endoderm Disease Modeling Human pluripotent stem cells pancreatic agenesis Cell Differentiation Cell Lineage Cells Cultured Endoderm GATA6 Transcription Factor Gene Regulatory Networks Homeodomain Proteins Humans Insulin-Secreting Cells Pancreas Pancreatic Diseases Pluripotent Stem Cells Protein Binding Smad2 Protein Smad3 Protein T-Box Domain Proteins Trans-Activators