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Cover Image for Modified platelet deposition on matrix metalloproteinase 13 digested collagen I. View Article
Modified platelet deposition on matrix metalloproteinase 13 digested collagen I.
J-M Howes, N Pugh, V Knäuper, RW Farndale
Sep 25, 2015
GPVI collagen receptor Collagen collagenase Matrix Metalloproteinase 13 platelets Blood Platelets Collagen Type I Electrophoresis Polyacrylamide Gel Humans Integrin alpha2beta1 Matrix Metalloproteinase 13 Platelet Adhesiveness Proteolysis Thrombosis
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Cover Image for MMP-13 binds to platelet receptors αIIbβ3 and GPVI and impairs aggregation and thrombus formation. View Article
MMP-13 binds to platelet receptors αIIbβ3 and GPVI and impairs aggregation and thrombus formation.
Joanna-Marie Howes, Nicholas Pugh, Samir W Hamaia, Stephanie M Jung, Vera Knäuper, Jean-Daniel Malcor, Richard W Farndale
Apr 26, 2018
BACKGROUND: Acute thrombotic syndromes lead to atherosclerotic plaque rupture with subsequent thrombus formation, myocardial infarction and stroke. Following rupture, flowing blood is exposed to plaque components, including...
GPVI collagen receptor Integrin alphaIIbbeta3 (αIIbβ3) matrix metalloproteinase‐13 platelets Thrombosis
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