Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci.
Hongjie Chen,
Shaoqi Fan,
Jennifer Stone,
Deborah J Thompson,
Julie Douglas,
Shuai Li,
Christopher Scott,
Manjeet K Bolla,
Qin Wang,
Joseph Dennis,
Kyriaki Michailidou,
Christopher Li,
Ulrike Peters,
John L Hopper,
Melissa C Southey,
Tu Nguyen-Dumont,
Tuong L Nguyen,
Peter A Fasching,
Annika Behrens,
Gemma Cadby,
Rachel A Murphy,
Kristan Aronson,
Anthony Howell,
Susan Astley,
Fergus Couch,
Janet Olson,
Roger L Milne,
Graham G Giles,
Christopher A Haiman,
Gertraud Maskarinec,
Stacey Winham,
Esther M John,
Allison Kurian,
Heather Eliassen,
Irene Andrulis,
D Gareth Evans,
William G Newman,
Per Hall,
Kamila Czene,
Anthony Swerdlow,
Michael Jones,
Marina Pollan,
Pablo Fernandez-Navarro,
Daniel S McConnell,
Vessela N Kristensen,
NBCS Investigators,
Joseph H Rothstein,
Pei Wang,
Laurel A Habel,
Weiva Sieh,
Alison M Dunning,
Paul Pharoah,
Douglas F Easton,
Gretchen L Gierach,
Rulla M Tamimi,
Celine M Vachon,
Sara Lindström
Apr 12, 2022
BACKGROUND: Mammographic density (MD) phenotypes, including percent density (PMD), area of dense tissue (DA), and area of non-dense tissue (NDA), are associated with breast cancer risk. Twin studies suggest that MD phenotypes...