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Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals
Byron Kuo, Marc A Beal, John W Wills, Paul A White, Francesco Marchetti, Andy Nong, Tara S Barton-Maclaren, Keith Houck, Carole L Yauk
Jun 07, 2022
Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learning
John W. Wills, Jatin R. Verma, Benjamin J. Rees, Danielle S. G. Harte, Qiellor Haxhiraj, Claire M. Barnes, Rachel Barnes, Matthew A. Rodrigues, Minh Doan, Andrew Filby, Rachel E. Hewitt, Catherine A. Thornton, James G. Cronin, Julia D. Kenny, Ruby Buckley, Anthony M. Lynch, Anne E. Carpenter, Huw D. Summers, George E. Johnson, Paul Rees
Aug 26, 2021
Abstract: The in vitro micronucleus assay is a globally significant method for DNA damage quantification used for regulatory compound safety testing in addition to inter-individual monitoring of environmental, lifestyle and...