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Drinking water from dug wells in rural ghana--salmonella contamination, environmental factors, and genotypes.
Denise Myriam Dekker, Ralf Krumkamp, Nimako Sarpong, Hagen Frickmann, Kennedy Gyau Boahen, Michael Frimpong, Renate Asare, Richard Larbi, Ralf Matthias Hagen, Sven Poppert, Wolfgang Rabsch, Florian Marks, Yaw Adu-Sarkodie, Jürgen May
Feb 19, 2019
Salmonellosis is an important but neglected disease in sub-Saharan Africa. Food or fecal-oral associated transmissions are the primary cause of infections, while the role of waterborne transmission is unclear. Samples were...
Characteristics and Risk Perceptions of Ghanaians Potentially Exposed to Bat-Borne Zoonoses through Bushmeat.
Alexandra O Kamins, J Marcus Rowcliffe, Yaa Ntiamoa-Baidu, Andrew A Cunningham, James LN Wood, Olivier Restif
Sep 18, 2014
Perceptions of governance and social capital in Ghana’s cocoa industry
Governance and social capital are significant components in the management and operation of agricultural value chains. We explore these related concepts by examining the regulator (COCOBOD) farmer dyad within the (Ghanaian)...
sustainability Social Capital Value Chains Socio-Economic Development Ghana Cocoa governance /dk/atira/pure/sustainabledevelopmentgoals/decent_work_and_economic_growth name=SDG 8 - Decent Work and Economic Growth /dk/atira/pure/sustainabledevelopmentgoals/peace_justice_and_strong_institutions name=SDG 16 - Peace, Justice and Strong Institutions
Producing molecular biology reagents without purification.
Sanchita Bhadra, Vylan Nguyen, Jose-Angel Torres, Shaunak Kar, Stéphane Fadanka, Chiara Gandini, Harry Akligoh, Inyup Paik, Andre C Maranhao, Jenny Molloy, Andrew D Ellington
Jul 02, 2021
We recently developed 'cellular' reagents-lyophilized bacteria overexpressing proteins of interest-that can replace commercial pure enzymes in typical diagnostic and molecular biology reactions. To make cellular reagent...
covid-19 COVID-19 Testing Cameroon Diagnostic Tests Routine Escherichia coli Gene Expression Geobacillus stearothermophilus Ghana Humans Indicators and Reagents Molecular Diagnostic Techniques Plasmids Real-Time Polymerase Chain Reaction Recombinant Proteins SARS-CoV-2 synthetic biology Transformation Bacterial United Kingdom
Evaluation of Typhoid Conjugate Vaccine Effectiveness in Ghana (TyVEGHA) Using a Cluster-Randomized Controlled Phase IV Trial
Andrea Haekyung Haselbeck, Birkneh Tilahun Tadesse, Juyeon Park, Malick M Gibani, Ligia María Cruz Espinoza, Ariane Abreu, Craig Van Rensburg, Michael Owusu-Ansah, Sampson Twuamsi-Ankrah, Michael Owusu, Isaac Aguna, Valentina Picot, Hyonjin Jeon, Ellen Higginson, Sunju Park, Zenaida R Mojares, Justin Im, Megan E Carey, Farhana Khanam, Susan Tonks, Gordon Dougan, Deokryun Kim, Jonathan Sugimoto, Vittal Mogasale, Kathleen M Neuzil, Firdausi Qadri, Yaw Adu-Sarkodie, Ellis Owusu-Dabo, John Clemens, Florian Marks
Jun 07, 2021
Typhoid fever remains a significant health problem in sub-Saharan Africa, with incidence rates of >100 cases per 100,000 person-years of observation. Despite the prequalification of safe and effective typhoid conjugate vaccines...
Health impacts of changes in travel patterns in Greater Accra Metropolitan Area, Ghana.
Leandro Garcia, Rob Johnson, Alex Johnson, Ali Abbas, Rahul Goel, Lambed Tatah, James Damsere-Derry, Elvis Kyere-Gyeabour, Marko Tainio, Thiago H de Sá, James Woodcock
Jun 28, 2021
BACKGROUND: Health impact assessments of alternative travel patterns are urgently needed to inform transport and urban planning in African cities, but none exists so far. OBJECTIVE: To quantify the health impacts of changes in...
Detection of Salmonella Typhi nucleic acid by RT-PCR and anti-HlyE, -CdtB, -PilL, and -Vi IgM by ELISA at sites in Ghana, Madagascar and Ethiopia.
Ursula Panzner, Ondari Daniel Mogeni, Yaw Adu-Sarkodie, Trevor Toy, Hyon Jin Jeon, Gi Deok Pak, Se Eun Park, Yeetey Enuameh, Ellis Owusu-Dabo, Trinh Van Tan, Abraham Aseffa, Mekonnen Teferi, Biruk Yeshitela, Stephen Baker, Raphael Rakotozandrindrainy, Florian Marks
Oct 02, 2022
BACKGROUND: We aimed to assess the prevalence of Salmonella Typhi through DNA and IgM-antibody detection methods as a prelude to extended surveillance activities at sites in Ghana, Madagascar, and Ethiopia. METHODS: We performed...
ELISA febrile illness HlyE-/CdtB-/PilL-/Vi-antigen salmonella SURVEILLANCE Adolescent Corneal Dystrophies Hereditary Enzyme-Linked Immunosorbent Assay Ethiopia Female Fever Ghana Humans Immunoglobulin M Madagascar Male Nucleic Acids Reverse Transcriptase Polymerase Chain Reaction salmonella Salmonella typhi Typhoid Fever
Covid-19 and school closure
The Covid-19 lockdown implemented globally to prevent the spread of the virus has led to the closure of schools. However, insight into the impact of the lockdown on private schools and the responses it has elicited is limited...
Characterization of Salmonella enterica from invasive bloodstream infections and water sources in rural Ghana.
Denise Dekker, Ralf Krumkamp, Daniel Eibach, Nimako Sarpong, Kennedy Gyau Boahen, Michael Frimpong, Elina Fechtner, Sven Poppert, Ralf Matthias Hagen, Norbert Georg Schwarz, Yaw Adu-Sarkodie, Ellis Owusu-Dabo, Justin Im, Florian Marks, Hagen Frickmann, Jürgen May
Sep 05, 2018
BACKGROUND: Non-typhoidal Salmonella (NTS) cause the majority of bloodstream infections in Ghana, however the mode of transmission and source of invasive NTS in Africa are poorly understood. This study compares NTS from water...
invasive non-typhoidal Salmonella transmission reservoir water sources ampicillin Anti-Bacterial Agents Bacteremia Child Drinking Water Drug Resistance Multiple Bacterial Ghana Humans Microbial Sensitivity Tests Rural Health Rural Population Salmonella Infections Salmonella enterica Trimethoprim Sulfamethoxazole Drug Combination Water Microbiology
Pseudomonas oryzihabitans sepsis in a 1-year-old child with multiple skin rashes
Michael Owusu, Ellis Owusu-Dabo, Godfred Acheampong, Isaac Osei, John Amuasi, Nimako Sarpong, Augustina Annan, Hsin-Ying Chiang, Chih-Horng Kuo, Se Eun Park, Florian Marks, Yaw Adu-Sarkodie
Feb 19, 2019
BACKGROUND: Pseudomonas oryzihabitans is a Pseudomonas bacterial organism rarely implicated in human infections. The bacterium has been isolated in a few reported cases of neurosurgical infections and patients with end-stage...
Full genomic characterization of a porcine rotavirus strain detected in an asymptomatic piglet in Accra, Ghana
Samuel C. B. Stubbs, Osbourne Quaye, Maame Ekua Acquah, Samuel Mawuli Adadey, Iain R. L. Kean, Srishti Gupta, Barbara A. Blacklaws
Jun 06, 2020
Abstract: Background: The introduction of rotavirus A vaccination across the developing world has not proved to be as efficacious as first hoped. One cause of vaccine failure may be infection by zoonotic rotaviruses that are...
Applying conditional process modelling to investigate factors influencing the adoption of water pollution mitigation behaviours
Abstract: Given that much of water resource pollution is behavioural in nature, understanding pro-environmental behaviour as well as the complex determinants of such behaviours is key to designing effective policies aimed at...
For the Environment
This article reflects critically on the impacts of the recent ban on artisanal and small-scale mining (ASM) – low-tech, labour-intensive mineral extraction and processing – in Ghana. Government officials claimed that a ban...
Artisanal and small-scale mining (ASM) Ghana informality Operation Vanguard /dk/atira/pure/subjectarea/asjc/1100/1107 name=Forestry /dk/atira/pure/subjectarea/asjc/3300/3305 name=Geography, Planning and Development /dk/atira/pure/subjectarea/asjc/2300/2309 name=Nature and Landscape Conservation /dk/atira/pure/subjectarea/asjc/2300/2308 name=Management, Monitoring, Policy and Law
Liver steatosis and fibrosis in people with human immunodeficiency virus in West Africa and the relationship with hepatitis B virus coinfection.
Giovanni Villa, Dorcas Owusu, Colette Smith, Marilyn Azumah, Adam Abdullahi, Suzannah Phillips, Laila Sayeed, Harrison Austin, David Chadwick, Richard Odame Phillips, Anna Maria Geretti
Sep 14, 2022
A Multicenter Cost-of-Illness and Long-term Socioeconomic Follow-up Study in the Severe Typhoid Fever in Africa Program
Enusa Ramani, Seeun Park, Trevor Toy, Ursula Panzner, Ondari D Mogeni, Justin Im, Ligia Maria Cruz Espinoza, Hyon Jin Jeon, Gi Deok Pak, Hyeongwon Seo, Yun Chon, Raphaël Rakotozandrindrainy, Ellis Owusu-Dabo, Isaac Osei, Abdramane Bassiahi Soura, Mekonnen Teferi, Florian Marks, Vittal Mogasale
Nov 26, 2019
BACKGROUND: There are limited data on typhoid fever cost of illness (COI) and economic impact from Africa. Health economic data are essential for measuring the cost-effectiveness of vaccination or other disease control...
What is stirring in the reservoir? Modelling mechanisms of henipavirus circulation in fruit bat hosts.
Emma E Glennon, Daniel J Becker, Alison J Peel, Romain Garnier, Richard D Suu-Ire, Louise Gibson, David TS Hayman, James LN Wood, Andrew A Cunningham, Raina K Plowright, Olivier Restif
Jun 20, 2019
Genetic characterization of varicella-zoster and HIV-1 viruses from the cerebrospinal fluid of a co-infected encephalitic patient, Ghana.
Philip El-Duah, Augustina Angelina Sylverken, Michael Owusu, Yaw Ampem Amoako, Richmond Yeboah, Richmond Gorman, Emmanuella Nyarko-Afriyie, Julia Schneider, Terry C Jones, Joseph Bonney, Titus Adade, Eric Smart Yeboah, Tabea Binger, Victor Max Corman, Christian Drosten, Richard Odame Phillips
Sep 02, 2022
SARS-COV-2 antibody responses to AZD1222 vaccination in West Africa.
Adam Abdullahi, David Oladele, Michael Owusu, Steven A Kemp, James Ayorinde, Abideen Salako, Douglas Fink, Fehintola Ige, Isabella ATM Ferreira, Bo Meng, Augustina Angelina Sylverken, Chika Onwuamah, Kwame Ofori Boadu, Kazeem Osuolale, James Opoku Frimpong, Rufai Abubakar, Azuka Okuruawe, Haruna Wisso Abdullahi, Gideon Liboro, Lawrence Duah Agyemang, Nana Kwame Ayisi-Boateng, Oluwatosin Odubela, Gregory Ohihoin, Oliver Ezechi, Japhet Senyo Kamasah, Emmanuel Ameyaw, Joshua Arthur, Derrick Boakye Kyei, Dorcas Ohui Owusu, Olagoke Usman, Sunday Mogaji, Adedamola Dada, George Agyei, Soraya Ebrahimi, Lourdes Ceron Gutierrez, Sani H Aliyu, Rainer Doffinger, Rosemary Audu, Richard Adegbola, Petra Mlcochova, Richard Odame Phillips, Babatunde Lawal Solako, Ravindra K Gupta
Nov 17, 2022
Real-world data on vaccine-elicited neutralising antibody responses for two-dose AZD1222 in African populations are limited. We assessed baseline SARS-CoV-2 seroprevalence and levels of protective neutralizing antibodies prior...
Towards Sustainable Urban Transportation in Ghana
RA Acheampong
Sep 12, 2017
Cycling is considered an environmentally-friendly mode of transport that offers many personal benefits including health, affordability and flexibility of travel. To encourage more people to cycle, especially in contexts where...
Human monkeypox - After 40 years, an unintended consequence of smallpox eradication.
Karl Simpson, David Heymann, Colin S Brown, W John Edmunds, Jesper Elsgaard, Paul Fine, Hubertus Hochrein, Nicole A Hoff, Andrew Green, Chikwe Ihekweazu, Terry C Jones, Swaib Lule, Jane Maclennan, Andrea McCollum, Barbara Mühlemann, Emily Nightingale, Dimie Ogoina, Adesola Ogunleye, Brett Petersen, Jacqueline Powell, Ollie Quantick, Anne W Rimoin, David Ulaeato, Andy Wapling
Sep 04, 2020
Smallpox eradication, coordinated by the WHO and certified 40 years ago, led to the cessation of routine smallpox vaccination in most countries. It is estimated that over 70% of the world's population is no longer protected...
Price Shocks and Human Capital
The effect of economic shocks on human capital is theoretically ambiguous due to opposing income and substitution effects. Using child level information on schooling, child labour, and cognitive development, we investigate the...
Ghana Cocoa Price Shocks child labour Schooling Cognitive development human capital /dk/atira/pure/sustainabledevelopmentgoals/no_poverty name=SDG 1 - No Poverty /dk/atira/pure/sustainabledevelopmentgoals/quality_education name=SDG 4 - Quality Education /dk/atira/pure/sustainabledevelopmentgoals/decent_work_and_economic_growth name=SDG 8 - Decent Work and Economic Growth
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