Homozygosity and risk of childhood death due to invasive bacterial disease.
Emily J Lyons,
William Amos,
James A Berkley,
Isaiah Mwangi,
Mohammed Shafi,
Thomas N Williams,
Charles R Newton,
Norbert Peshu,
Kevin Marsh,
J Anthony G Scott,
Adrian VS Hill
Jun 14, 2011
BACKGROUND: Genetic heterozygosity is increasingly being shown to be a key predictor of fitness in natural populations, both through inbreeding depression, inbred individuals having low heterozygosity, and also through chance...