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Uncovering correlated variability in epigenomic datasets using the Karhunen-Loeve transform.
Pedro Madrigal
,
Paweł Krajewski
Jun 19, 2020
BACKGROUND: Larger variation exists in epigenomes than in genomes, as a single genome shapes the identity of multiple cell types. With the advent of next-generation sequencing, one of the key problems in computational...
ChIP-seq
Functional data analysis
H1
H2A.Z
H3K36me3
H3K4me3
H3K9ac
Histone modifications
Roadmap Epigenomics Consortium
Stem Cells
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