Independence of HIF1a and androgen signaling pathways in prostate cancer.
Maxine GB Tran,
Becky AS Bibby,
Lingjian Yang,
Franklin Lo,
Anne Y Warren,
Deepa Shukla,
Michelle Osborne,
James Hadfield,
Thomas Carroll,
Rory Stark,
Helen Scott,
Antonio Ramos-Montoya,
Charlie Massie,
Patrick Maxwell,
Catharine ML West,
Ian G Mills,
David E Neal
Jul 14, 2020
BACKGROUND: Therapeutic targeting of the androgen signaling pathway is a mainstay treatment for prostate cancer. Although initially effective, resistance to androgen targeted therapies develops followed by disease progression to...