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A fusion intermediate gp41 immunogen elicits neutralizing antibodies to HIV-1.
Rachel PJ Lai, Miriam Hock, Jens Radzimanowski, Paul Tonks, David Lutje Hulsik, Gregory Effantin, David J Seilly, Hanna Dreja, Alexander Kliche, Ralf Wagner, Susan W Barnett, Nancy Tumba, Lynn Morris, Celia C LaBranche, David C Montefiori, Michael S Seaman, Jonathan L Heeney, Winfried Weissenhorn
Mar 11, 2016
AIDS HIV-1 HIV-1 gp41 Membrane Fusion Protein Conformation Vaccine Development X-ray Scattering Amino Acid Sequence Animals Antibodies Neutralizing Antibody Affinity Female Guinea Pigs HIV Antibodies HIV Envelope Protein gp41 Humans Immune Sera Immunization Immunoglobulin G Molecular Sequence Data neutron diffraction Protein Structure Tertiary Proteolipids SCATTERING Small Angle