KIR Variation in Iranians Combines High Haplotype and Allotype Diversity With an Abundance of Functional Inhibitory Receptors
Claudia Alicata,
Elham Ashouri,
Neda Nemat-Gorgani,
Lisbeth A. Guethlein,
Wesley M. Marin,
Sudan Tao,
Lorenzo Moretta,
Jill A. Hollenbach,
John Trowsdale,
James A. Traherne,
Abbas Ghaderi,
Peter Parham,
Paul J. Norman
Apr 16, 2020
Natural killer (NK) cells are innate lymphocytes that eliminate infected and transformed cells. They discriminate healthy from diseased tissue through killer cell Ig-like receptor (KIR) recognition of HLA class I ligands....