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The impact of hypertonic saline on cerebrovascular reactivity and compensatory reserve in traumatic brain injury
Logan Froese, Joshua Dian, Carleen Batson, Alwyn Gomez, Bertram Unger, Frederick A Zeiler
Oct 23, 2020
BACKGROUND: Intravenous hypertonic saline is utilized commonly in critical care for treatment of acute or refractory elevations of intracranial pressure (ICP) in traumatic brain injury (TBI) patients. Though there is a clear...
Cerebrovascular Circulation cerebrovascular response Hypertonic saline Intracranial Pressure pressure reactivity index Sodium Chloride Adult Arterial Pressure Brain Injuries Traumatic Cerebrovascular Circulation Female Hemodynamics Humans Intracranial Hypertension Intracranial Pressure Male Middle Aged Retrospective Studies Saline Solution Hypertonic Young Adult
Early Osmotherapy in Severe Traumatic Brain Injury
James R Anstey, Fabio S Taccone, Andrew A Udy, Giuseppe Citerio, Jacques Duranteau, Carole Ichai, Rafael Badenes, John R Prowle, Ari Ercole, Mauro Oddo, Antoine G Schneider, Mathieu van der Jagt, Stefan Wolf, Raimund Helbok, David W Nelson, Marius B Skrifvars, Anatole Harrois, Jeffrey Presneill, D Jamie Cooper, Michael Bailey, Rinaldo Bellomo, TBI Collaborative
Jul 02, 2019
The optimal osmotic agent to treat intracranial hypertension in patients with severe traumatic brain injury (TBI) remains uncertain. We aimed to test whether the choice of mannitol or hypertonic saline (HTS) as early (first...