Estimands and their Estimators for Clinical Trials Impacted by the COVID-19 Pandemic
Kelly Van Lancker,
Sergey Tarima,
Jonathan Bartlett,
Madeline Bauer,
Bharani Bharani-Dharan,
Frank Bretz,
Nancy Flournoy,
Hege Michiels,
Camila Olarte Parra,
James L Rosenberger,
Suzie Cro
Dec 31, 2023
The COVID-19 pandemic continues to affect the conduct of clinical trials globally. Complications may arise from pandemic-related operational challenges such as site closures, travel limitations and interruptions to the supply...