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An evaluation of purified Salmonella Typhi protein antigens for the serological diagnosis of acute typhoid fever.
Nga Tran Vu Thieu, Tan Trinh Van, Anh Tran Tuan, Elizabeth J Klemm, Chau Nguyen Ngoc Minh, Phat Voong Vinh, Duy Pham Thanh, Thanh Ho Ngoc Dan, Trung Pham Duc, Pinky Langat, Laura B Martin, Jorge Galan, Li Liang, Philip L Felgner, D Huw Davies, Hanna K de Jong, Rapeephan R Maude, Masako Fukushima, Lalith Wijedoru, Aniruddha Ghose, Rasheda Samad, Arjen M Dondorp, Abul Faiz, Thomas C Darton, Andrew J Pollard, Guy E Thwaites, Gordon Dougan, Christopher M Parry, Stephen Baker
Apr 10, 2019
OBJECTIVES: The diagnosis of typhoid fever is a challenge. Aiming to develop a typhoid diagnostic we measured antibody responses against Salmonella Typhi (S. Typhi) protein antigens and the Vi polysaccharide in a cohort of...