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Three-dimensional imaging mass cytometry for highly multiplexed molecular and cellular mapping of tissues and the tumor microenvironment
L Kuett, R Catena, A Özcan, A Plüss, HR Ali, MA Sa’d, S Alon, S Aparicio, G Battistoni, S Balasubramanian, R Becker, B Bodenmiller, ES Boyden, D Bressan, A Bruna, M Burger, C Caldas, M Callari, IG Cannell, H Casbolt, N Chornay, Y Cui, A Dariush, K Dinh, A Emenari, Y Eyal-Lubling, J Fan, A Fatemi, E Fisher, EA González-Solares, C González-Fernández, D Goodwin, W Greenwood, F Grimaldi, GJ Hannon, S Harris, C Jauset, JA Joyce, ED Karagiannis, T Kovačević, R Kunes, AK Yoldaş, D Lai, E Laks, H Lee, M Lee, G Lerda, Y Li, A McPherson, N Millar, CM Mulvey, I Nugent, CH O’Flanagan, M Paez-Ribes, I Pearsall, F Qosaj, AJ Roth, OM Rueda, T Ruiz, K Sawicka, LA Sepúlveda, SP Shah, A Shea, A Sinha, A Smith, S Tavaré, S Tietscher, I Vázquez-García, SL Vogl, NA Walton, AT Wassie, SS Watson, J Weselak, SA Wild, E Williams, J Windhager, C Xia, P Zheng, X Zhuang, P Schraml, H Moch, N de Souza, B Bodenmiller
Jan 28, 2022
A holistic understanding of tissue and organ structure and function requires the detection of molecular constituents in their original three-dimensional (3D) context. Imaging mass cytometry (IMC) enables simultaneous detection...
Metamorphosis of an identified serotonergic neuron in the Drosophila olfactory system.
Bidisha Roy, Ajeet P Singh, Chetak Shetty, Varun Chaudhary, Annemarie North, Matthias Landgraf, K Vijayraghavan, Veronica Rodrigues
Jun 16, 2011
Animals Cell Differentiation Cell Shape Central Nervous System Dendrites Drosophila Proteins Drosophila melanogaster Ecdysterone Feedback Growth Cones Image Cytometry Larva Metamorphosis Biological Microtubule-Associated Proteins Mushroom Bodies Nerve Net Neuronal Plasticity Olfactory Pathways Receptors Steroid Sensory Receptor Cells Serotonin Smell
Rapid patterning of 1-D collagenous topography as an ECM protein fibril platform for image cytometry.
Niannan Xue, Xia Li, Cristina Bertulli, Zhaoying Li, Atipat Patharagulpong, Amine Sadok, Yan Yan Shery Huang
Jan 16, 2018
Cellular behavior is strongly influenced by the architecture and pattern of its interfacing extracellular matrix (ECM). For an artificial culture system which could eventually benefit the translation of scientific findings into...
Imaging mass cytometry and multiplatform genomics define the phenogenomic landscape of breast cancer
H Raza Ali, Hartland W Jackson, Vito RT Zanotelli, Esther Danenberg, Jana R Fischer, Helen Bardwell, Elena Provenzano, Oscar M Rueda, Suet-Feung Chin, Samuel Aparicio, Carlos Caldas, Bernd Bodenmiller
Mar 11, 2020
Genomic alterations shape cell phenotypes and the structure of tumor ecosystems in poorly defined ways. To investigate these
relationships, we used imaging mass cytometry to quantify the expression of 37 proteins with...