Search

BACKGROUND: Mesothelioma is an incurable cancer originating from the mesothelial cells that line the pleural, peritoneal and pericardial cavities. These cells synthesise large quantities of surface glycoproteins, rendering them...

Biomarkers Tumor Cell Differentiation Endoplasmic Reticulum Chaperone BiP Endoplasmic reticulum stress Female Follow-Up Studies HEAT-SHOCK PROTEINS Humans Immunoenzyme Techniques Male Mesothelioma Neoplasm Staging Prognosis Protein Phosphatase 1 Signal Transduction Survival Rate Tissue Array Analysis Transcription Factor CHOP

The accumulation of β-amyloid (Aβ) peptide in the brain is one of the pathological hallmarks of Alzheimer's disease and is thought to be of primary aetiological significance. In an unbiased genetic screen, we identified...

Alzheimer Amyloid Autophagy Proteolysis Puromycin-sensitive aminopeptidase Alzheimer Disease Aminopeptidases Amyloid beta-Peptides Animals Animals Genetically Modified Autophagy Blotting Western Brain Drosophila melanogaster Enzyme-Linked Immunosorbent Assay Flow Cytometry Fluorescent Antibody Technique Humans Immunoenzyme Techniques Neuroblastoma Neurons Proteolysis puromycin RNA Messenger Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction Tumor Cells Cultured

Adult Aged Aged 80 and over Breast Neoplasms CD146 Antigen Cell Movement Female Flow Cytometry Gene Expression Profiling Gene Expression Regulation Neoplastic Gene Silencing Humans Immunoenzyme Techniques Mesoderm Middle Aged Oligonucleotide Array Sequence Analysis Prognosis RNA Messenger RNA Small Interfering Reverse Transcriptase Polymerase Chain Reaction Tissue Array Analysis Tumor Cells Cultured Young Adult

CD274 PD-L1 basal-like Breast Cancer immune checkpoint Lymphocytes B7-H1 Antigen Biomarkers Tumor Breast Neoplasms Carcinoma Basal Cell Female Follow-Up Studies Humans Immunoenzyme Techniques Lymphocytes Tumor-Infiltrating Neoplasm Staging Observational Studies as Topic Prognosis Randomized Controlled Trials as Topic Tissue Array Analysis

The importance of epigenetic changes in the development of hepatic steatosis is largely unknown. The histone variant macroH2A1 under alternative splicing gives rise to macroH2A1.1 and macroH2A1.2. In this study, we show that the...

bivalent promoter histone methylation histone variants Lipid uptake Animals Biomarkers Blotting Western Carcinoma Hepatocellular Cells Cultured Chromatin Immunoprecipitation Diet High-Fat Epigenomics Fatty Liver Female Fluorescent Antibody Technique Gene Expression Profiling Hepatocytes Histones Humans Immunoenzyme Techniques Lipid Peroxidation Liver Liver Neoplasms Male Mice Mice Inbred C57BL Mice Knockout Mitochondrial Proton-Translocating ATPases Oligonucleotide Array Sequence Analysis Promoter Regions Genetic Protein Isoforms RNA Messenger Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction

Analyzer feline human hyperthyroidism reference interval Animals Cat Diseases Cats Female Hyperthyroidism Immunoenzyme Techniques Male Radioimmunoassay Reference Values Reproducibility of Results Thyroid Function Tests Thyroxine

We assessed the presence of vascular endothelial growth factor (VEGF)-C, VEGF-D and their receptor VEGFR-3 by immunohistochemistry in 59 epithelial ovarian carcinomas, 11 borderline tumours and 20 benign cystadenomas. VEGF-C and...

Adenocarcinoma Clear Cell Adenocarcinoma Mucinous Adult Aged Biomarkers Tumor Cystadenocarcinoma Serous Endothelial Growth Factors Female Humans Immunoenzyme Techniques Lymphatic Metastasis Middle Aged Neoplasms Glandular and Epithelial Ovarian Neoplasms Peritoneal Neoplasms Prognosis Retrospective Studies Vascular Endothelial Growth Factor C Vascular Endothelial Growth Factor D Vascular Endothelial Growth Factor Receptor-3

Adenocarcinoma Animals Apoptosis Biomarkers Tumor Blotting Western Carcinogenesis Carcinoma Non-Small-Cell Lung Cell Proliferation Disease Progression Gene Expression Regulation Neoplastic Humans Immunoenzyme Techniques Lung Neoplasms Male Mice Mice Inbred NOD Mice SCID MicroRNAs Mitogen-Activated Protein Kinase 14 Neoplastic Stem Cells RNA Long Noncoding RNA Messenger Real-Time Polymerase Chain Reaction Receptors G-Protein-Coupled Reverse Transcriptase Polymerase Chain Reaction Signal Transduction Tumor Cells Cultured Wnt Proteins Xenograft Model Antitumor Assays

Hypoxia Kidney oxygen sensing Animals Anoxia Dietary Supplements Epoetin Alfa Erythropoiesis Erythropoietin Hemoglobins Hypoxia-Inducible Factor 1 alpha Subunit Immunoenzyme Techniques Kidney Liver Male Nitrates Oxygen Rats Rats Wistar Recombinant Proteins