In vivo alpha-V beta-3 integrin expression in human aortic atherosclerosis.
William S Jenkins,
Alex T Vesey,
Anna Vickers,
Anoushka Neale,
Catriona Moles,
Martin Connell,
Nikhil Vilas Joshi,
Christophe Lucatelli,
Alison M Fletcher,
James C Spratt,
Saeed Mirsadraee,
Edwin JR van Beek,
James HF Rudd,
David E Newby,
Marc R Dweck
Jul 24, 2019
OBJECTIVES: Intraplaque angiogenesis and inflammation are key promoters of atherosclerosis and are mediated by the alpha-V beta-3 (αvβ3) integrin pathway. We investigated the applicability of the αvβ3-integrin receptor-selective...