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Alpha-synuclein (α-syn) is a small protein that, in neurons, localizes predominantly to presynaptic terminals. Due to elevated conformational plasticity, which can be affected by environmental factors, in addition to undergoing...

conformational plasticity Interactome synaptic proteins Synucleinopathies α-synuclein Animals Humans Multiple System Atrophy Neurotransmitter Agents Parkinson Disease Protein Binding Synapses ALPHA-SYNUCLEIN

Signal peptide peptidase Vigilin Biochemistry Intramembrane-cleaving aspartyl protease Non-proteolytic function Interactome

The intracellular functions of myosin motors requires a number of adaptor molecules, which control cargo attachment, but also fine-tune motor activity in time and space. These motor-adaptor-cargo interactions are often weak...

BioID MYO6 endosome functional proteomics Interactome Actin Cytoskeleton Carrier Proteins Cytoskeleton Endosomes Humans Models Biological Multiprotein Complexes Mutation Myosin Heavy Chains Protein Binding Protein Interaction Mapping Protein Interaction Maps