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This paper considers the problem of semi-parametric proportional hazards model fitting where observed survival times contain event times and also interval, left and right censoring times. Although this is not a new topic, many...

asymptotic properties automated smoothing constrained optimization Interval censoring semi-parametric proportional hazard model Proportional Hazards Models Likelihood Functions Computer Simulation Algorithms Research Design

In psoriatic arthritis, permanent joint damage characterizes disease progression and represents a major debilitating aspect of the disease. Understanding the process of joint damage will assist in the treatment and disease...

Bradford Hill criteria Causality Composable Markov process damage disease activity Dynamic modelling Granger causality and non-causality Interval censoring Local dependence and independence Multistate models psoriatic arthritis Random effect Robust information sandwich estimator temporality